Table 1.

The results of the Poisson models, including cadmium concentration, age class, sex, neuter status, and investigated year.

Variable	PMRs proportional morbility ratios (95% CI)
	Mammary gland tumors response		Soft tissue tumors response		Skin tumors response
	Univariate	Multivariate	Univariate	Multivariate	Univariate	Multivariate
Cd low polluted area	Ref.	Ref.	Ref.	Ref.	Ref.	Ref.
Cd high polluted area	42.61 (29.94–60.65)	44.94 (31.45–64.22)	66.81 (48.80–91.47)	56.28 (40.94–77.35)	78.34 (60.14–102.05)	80.13 (61.09–105.11)
0–4 years old	Ref.	Ref.	Ref.	Ref.	Ref.	Ref.
5–8 years old	1.08 (0.60–1.96)	1.00 (0.56–1.78)	1.62 (0.97–2.69)	1.46 (0.87–2.43)	1.16 (0.72–1.88)	1.21 (0.76–1.91)
9–12 years old	1.41 (0.82–2.41)	1.35 (0.79–2.30)	1.18 (0.72–1.94)	1.10 (0.67–1.81)	0.99 (0.63–1.55)	1.06 (0.69–1.64)
13–16 years old	1.28 (0.74–2.20)	1.25 (0.73–2.14)	0.85 (0.51–1.41)	0.85 (0.51–1.41)	0.91 (0.57–1.43)	0.95 (0.61–1.48)
17–20 years old	1.20 (0.66–2.18)	1.18 (0.66–2.14)	0.43 (0.22–0.86)	0.53 (0.27–1.05)	1.13 (0.68–1.88)	1.18 (0.72–1.92)
Male	–	–	Ref.	Ref.	Ref.	Ref.
Female	–	–	0.57 (0.46–0.70)	0.60 (0.48–0.74)	0.63 (0.51–0.76)	0.65 (0.54–0.79)
Not neutered	Ref.	Ref.	Ref.	Ref.	Ref.	Ref.
Neutered	0.58 (0.47–0.72)	0.53 (0.43–0.64)	1.56 (1.15–2.11)	2.26 (1.86–2.73)	1.25 (0.97–1.63)	1.16 (0.89–1.51)
2002–2006	Ref.	Ref.	Ref.	Ref.	Ref.	Ref.
2007–2011	0.87 (0.64–1.18)	0.93 (0.69–1.26)	0.46 (0.31–0.68)	0.61 (0.41–0.91)	0.87 (0.63–1.20)	1.11 (0.81–153)
2012–2016	0.80 (0.59–1.07)	0.83 (0.61–1.11)	0.34 (0.22–0.52)	0.46 (0.29–0.71)	0.97 (0.73–1.31)	1.22 (0.91–1.63)
2017–2022	0.90 (0.58–1.41)	0.86 (0.55–1.33)	0.22 (0.10–0.47)	0.24 (0.11–0.51)	2.00 (1.46–2.75)	1.97 (1.47–2.64)