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. 2024 Jul 17;39(6):1149–1155. doi: 10.1007/s11011-024-01380-1

Table 2.

The Danish (n = 200) linear regression equations for each subtest used for PHES calculation. The data were all log-transformed to achieve normal distribution, except for the LTT errors, which were square root transformed, and the SDT, which was log-log transformed. The data demonstrates the impact of age, sex, and education on each subtest

Subtest Constant Age Sex Education Standard deviation of residuals Interpretation
Female vs male 13–19 years vs others
NCTA 2.63 0.015 -0.123 -0.214 0.373

NCT A time increases with age

Females are faster than males

People with longer education are faster

NCTB 3.61 0.014 -0.129 -0.224 0.266

NCT B time increases with age

Females are faster than males

People with longer education are faster

LTT time 3.84 0.007 0 -0.134 0.309

LTT time increases with age

There is no effect of sex

People with longer education are faster

LTT error 3.25 0.039 0 0 1.963

LT errors increase with age

There is no effect sex and education

DSTa 4.13 -0.007 0.123 0.136 0.167

Fewer boxes are filled with increasing age

Females and people with longer education fill more boxes

SDT 1.25 0.002 0

- 0.041b

- 0.054

0.053

SDT time increases with age

There is no effect of sex

People with longer education are faster

Abbreviations: Portosystemic Hepatic Encephalopathy Score (PHES), Number Connection Test A (NCT-A), Number Connection Test B (NCT-B), Line Tracing Test time (LTT time), Line Tracing Test errors (LTT errors), Digit Symbol Test (DST), Serial Dotting Test (SDT)

aOperational sign is opposite the other subtests because DST is better the higher it gets (boxes filled)

b10–12 years versus others