Table 1.
Demographic information of BC-GENIST cohort.
| Total N (%) | 74 (100.0) | |
|---|---|---|
| Maternal age (yr) | Mean (SD) | 34.2 (4.0) |
| Pre-pregnancy BMI | Mean (SD) | 20.7 (2.6) |
| Prenatal vitamin usage, N (%) | Yes | 52 (70.3) |
| Fetal sex, N (%) | Female | 40 (54.1) |
| Gestational age at delivery (weeks) | Mean (SD) | 39.1 (1.2) |
| Gestational age at T1 | Mean (SD) | 19.0 (4.5) |
| Serum vitamin D concentration (ng/mL) at T1 | Mean (SD) | 25.2 (11.8) |
| Gestational age at T2 | Mean (SD) | 35.9 (0.9) |
| Serum vitamin D concentration (ng/mL) at T2 | Mean (SD) | 28.0 (14.4) |
| Estimated dietary vitamin D intake per day | Mean (SD) | 5.1 (4.4) |
| Maternal serum vitamin D deficiency levels, N (%)☨ | Deficient | 8 (10.8) |
| Insufficient | 20 (27.0) | |
| Sufficient | 46 (62.2) | |
| Estimated immune proportions from cord blood DNA methylation profiles | ||
| CD8 T cell | Mean (SD) | 5.23(3.35) |
| CD4 T cell | Mean (SD) | 19.25(7.15) |
| NK cell | Mean (SD) | 0.71(1.24) |
| B cell | Mean (SD) | 6.67(2.84) |
| Monocyte | Mean (SD) | 3.15(2.27) |
| Granulocyte | Mean (SD) | 61.46(9.2) |
| Nucleated red blood cell (nRBC) | Mean (SD) | 4.09(3.26) |
☨Deficient, both T1 and T2 serum vitamin D concentrations were less than 20 ng/mL; insufficient, one of the measurements was less than 20 ng/mL and the other was less than 30 ng/mL.