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Comparison of LBT-999 accumulation in rat brain using Q-TOF/TQ and DESI. A and B images of brain sagittal slices and spectra obtained in MS mode (m/z 332.1) and MS/MS mode (m/z 154.1), respectively using a Xevo G2-XS QTOF mass spectrometer from a rat injected with 2 mg/kg of LBT-999. C and D images of brain sagittal slices obtained using a Xevo TQ-XS MS spectrometer in MRM mode (332.1 > 154.1) from rats injected with LBT-999 at 2 and 0.02 mg/kg, respectively. Spatial resolution 100 µm
