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. 2024 Aug 5;154(3):e2024065650. doi: 10.1542/peds.2024-065650

TABLE 2.

Frequency of Neurodevelopmental and Other Mental Health Diagnoses in CMC and in the Reference Population of Children Without Medical Complexity

Non-CMC, n = 865 451 CMC, n = 85 581 Risk Ratioa (95% CI)
At least 1 neurodevelopmental or other mental health condition 181 709 (21.0%) 50 848 (59.4%) 2.51 (2.48–2.53)
≥1 Neurodevelopmental conditions 100 849 (11.7%) 39 065 (45.6%) 3.46 (3.42–3.50)
 Attention-deficit hyperactivity disorder 66 973 (7.0%) 20 171 (23.6%) 2.63 (2.58–2.67)
 Developmental delay or unspecified neurodevelopmental disorder 14 132 (1.6%) 13 534 (15.8%) 8.42 (8.22–8.62)
 Specific learning disorders 12 697 (1.5%) 8793 (10.3%) 6.61 (6.43–6.80)
 Autism spectrum disorder 13 389 (1.5%) 8045 (9.4%) 5.46 (5.31–5.61)
 Communication disorders 9325 (1.1%) 4957 (5.8%) 5.36 (5.17–5.55)
 Intellectual disability 7061 (0.8%) 6281 (7.3%) 7.25 (7.01–7.50)
 Motor disorders 4062 (0.5%) 2624 (3.1%) 6.38 (6.07–6.71)
 Neurocognitive disorders 2929 (0.3%) 2206 (2.6%) 6.46 (6.11–6.83)
≥1 Mental health conditions 126 046 (14.6%) 31 703 (37.0%) 2.22 (2.19–2.24)
 Trauma and stressor-related disorders 59 915 (6.9%) 12 297 (14.4%) 1.80 (1.77–1.84)
 Anxiety disorders 41 238 (4.8%) 11 763 (13.7%) 2.52 (2.47–2.57)
 Disruptive, impulse control, and conduct disorders 27 051 (3.1%) 9334 (10.9%) 2.95 (2.88–3.02)
 Depressive disorders 23 808 (2.8%) 7825 (9.1%) 2.54 (2.47–2.60)
 Miscellaneousb 18 744 (2.2%) 7417 (8.7%) 3.19 (3.11–3.28)
 Mental health symptomsc 9557 (1.1%) 4396 (5.1%) 4.04 (3.90–4.19)
 Elimination disorders 4240 (0.5%) 2161 (2.5%) 4.94 (4.69–5.20)
 Bipolar and related disorders 2856 (0.3%) 1445 (1.7%) 3.85 (3.61–4.10)
 Suicide or self-injury 2376 (0.3%) 1153 (1.3%) 3.63 (3.39–3.90)
 Obsessive–compulsive and related disorders 2277 (0.3%) 969 (1.1%) 3.78 (3.51–4.08)
 Schizophrenia spectrum and other psychotic disorders 2031 (0.2%) 1356 (1.6%) 5.06 (4.72–5.42)
 Feeding and eating disorders 1023 (0.1%) 1280 (1.5%) 11.12 (10.23–12.09)
 Somatic symptom and related disorders 660 (0.1%) 819 (1.0%) 10.83 (9.76–12.01)
 Otherd 2665 (0.3%) 1351 (1.6%) 4.44 (4.15–4.75)
No. unique neurodevelopmental disorders and/or mental health conditions
 0 683 726 (79.0%) 34 701 (40.6%) 0.50 (0.49–0.50)
 1 104 097 (12.0%) 18 075 (21.1%) 1.59 (1.57–1.62)
 2 41 398 (4.8%) 12 803 (15.0%) 2.76 (2.70–2.81)
 3 18 846 (2.2%) 8310 (9.7%) 3.84 (3.74–3.94)
 ≥4 17 384 (2.0%) 11 692 (13.7%) 5.64 (5.50–5.77)

All groups of neurodevelopmental and mental health diagnoses are based on the CAMHD-CS. A child can have zero or multiple diagnoses.

a

Adjusted for age, sex, payer, rurality, state, and months of health care enrollment or claims in the diagnosis ascertainment period.

b

Most common ICD-9/10 codes included within the miscellaneous group are unspecified episodic mood disorder (5224 [46.4%] CMC; 12 750 [68.1%] in the reference population), unspecified nonpsychotic mental disorder (1889 [25.5%] CMC; 3523, 18.8% in the reference population), and other emotional disturbances of childhood and adolescence (970 [8.6%] CMC; 2601 [13.9%] in the reference population), accounting for 6069 (81.8%) of CMC and 15 187, 81.0% of children in the reference population included in this category.

c

Most common ICD-9/10 codes included within the mental health symptoms are unspecified mental or behavioral problem (1635 [37.2%] CMC; 4559 [47.7%] in the reference population), other and unspecified special symptoms or syndromes, not elsewhere classified (1497 [34.1%] CMC; 2719 [28.5%] in the reference population), and attention or concentration deficit (549 [12.5%] CMC; 1444 [15.1%] in the reference population), accounting for 3289 (74.8%) of CMC and 7939 (83.1%) of children in the reference population.

d

Other includes the following groups, combined because of small cell sizes: fetal or newborn damage related to maternal substance abuse, maternal mental illness or substance abuse during pregnancy, delivery, or postpartum, personality disorders, sexuality and gender identity disorders, sleep–wake disorders, substance abuse-related medical illness, substance-related and addictive disorders, and accidental or undetermined poisoning.