Table 1. Peptide substrate cleavage by recombinant hTACE forms.
TACE form | kcat/Km peptide (M−1·s−1) |
---|---|
hR473 wild-type | 1.09×106±0.54×105 |
hR473 C184A | 1.78×105±0.20×105 |
hR651 wild-type | 1.69×105±0.18×105 |
hR651 C184A | 9.93×104±0.54×104 |
TACE form | kcat/Km peptide (M−1·s−1) |
---|---|
hR473 wild-type | 1.09×106±0.54×105 |
hR473 C184A | 1.78×105±0.20×105 |
hR651 wild-type | 1.69×105±0.18×105 |
hR651 C184A | 9.93×104±0.54×104 |