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. 2024 Aug 16;14(16):2379. doi: 10.3390/ani14162379

Table 1.

Differentially expressed genes up- and downregulated in WS-affected broilers, according to FDR (novel genes associated with white striping are shown in bold).

Upregulated
Chromosome Associated Gene Name Gene Description Ensembl Gene Id logFC FDR
2 PDK4 pyruvate dehydrogenase kinase 4 ENSGALG00010002741 3.41421 1.571 × 10−24
1 MYBPC1 myosin binding protein C1 ENSGALG00010011558 2.75445 8.349 × 10−17
26 FKBP5 FK506 binding protein 5 ENSGALG00010026893 2.40214 1.345 × 10−12
2 CEBPD CCAAT enhancer binding protein delta ENSGALG00010005405 2.01735 7.776 × 10−9
2 CA3A carbonic anhydrase 3A ENSGALG00010013288 2.00895 7.776 × 10−9
26 TNNT2 troponin T2, cardiac type ENSGALG00010026743 1.57929 3.182 × 10−5
2 ASNS asparagine synthetase (glutamine-hydrolyzing) ENSGALG00010003382 1.52297 9.686 × 10−5
1 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 ENSGALG00010006245 1.45674 0.0002375
1 NELL2 neural EGFL like 2 ENSGALG00010013749 1.43497 0.0006832
2 FBXO32 F-box protein 32 ENSGALG00010008245 1.37948 0.0006832
3 SESN1 sestrin 1 ENSGALG00010014244 1.34848 0.0009661
3 TDH L-treonina desidrogenase ENSGALG00010011278 1.23466 0.0064443
4 MYOZ2 myozenin 2 ENSGALG00010005510 1.21752 0.0089447
4 COL4A6 collagen type IV alpha 6 chain ENSGALG00010015733 1.20722 0.0107838
4 FHL1 four and a half LIM domains 1 ENSGALG00010014929 1.20013 0.0088713
9 CHRNG cholinergic receptor nicotinic gamma subunit ENSGALG00010017878 1.18978 0.0143605
5 ASB2 ankyrin repeat and SOCS box containing 2 ENSGALG00010016987 1.17026 0.0122158
4 COL4A5 collagen type IV alpha 5 chain ENSGALG00010015632 1.14888 0.0228397
5 MYBPC3 myosin binding protein C3 ENSGALG00010022468 1.14728 0.0190541
28 ARRDC2 arrestin domain containing 2 ENSGALG00010027232 1.14249 0.0216413
1 UCP3 uncoupling protein 3 ENSGALG00010002543 1.08505 0.0337988
6 DDIT4 DNA damage inducible transcript 4 ENSGALG00010021509 1.0787 0.0370386
1 RGCC regulator of cell cycle ENSGALG00010003192 1.07199 0.0372903
Downregulated
Chromosome Associated gene name Gene description Ensembl gene id logFC FDR
1 METTL21EP methyltransferase like 21E, pseudogene ENSGALG00010006037 −2.2487 1.40 × 10−10
3 UBE3D ubiquitin protein ligase E3D ENSGALG00010003115 −2.0996 4.26 × 10−9
6 SCD stearoyl-CoA desaturase ENSGALG00010021083 −1.9290 3.38 × 10−8
1 DGAT2 diacylglycerol O-acyltransferase 2 ENSGALG00010003035 −1.5278 9.69 × 10−5
5 DUSP8 dual specificity phosphatase 8 ENSGALG00010024637 −1.3427 0.0017
Z LIPG lipase G, endothelial type ENSGALG00010009013 -1.0878 0.0466
3 ATF3 activating transcription factor 3 ENSGALG00010019307 −1.0621 0.0431