Table 1.

Case Characteristics

Case no.	Surgical procedure	Histology	Frozen section margin analysis	Turn‐around time, min	AR‐guided intraoperative consultation	Final margin status
1	Hemiglossectomy	SCC	NEGATIVE Anterior tongue (−) 7 mm from margin Lateral tongue (−)	18	Discussion of specimen orientation/margin sampling sites using 3D hologram.	NEGATIVE Closest margin: lateral, 6 mm.
2	Floor of mouth excision	SCC	NEGATIVE Ventral tongue (−): focal severe dysplasia Dorsal tongue (−): focal severe dysplasia Anterior tongue (−) Mandibular alveolar ridge (−)	36	Discussion of specimen orientation/margin sampling sites using 3D hologram.	NEGATIVE All resection margins negative for malignancy.
3	Floor of mouth excision	SCC	POSITIVE Anterior mucosal (+): papillary SCC at margin Lateral mandibular alveolar ridge (−)	26	Discussion of specimen orientation/margin sampling sites using 3D hologram.	NEGATIVE Anterior re‐resection negative for malignancy.
4	Upper lip resection, partial rhinectomy	Basosquamous carcinoma	NEGATIVE Nasal septal (−) Nasal floor (−) Upper lip and nose (−)	37	Discussion of 2 perpendicular and 1 shave margin sites. Displayed 3D mapped specimen. Displayed 2D H&E image of closest margin (upper lip).	POSITIVE Focally positive along superomedial aspect adjacent to the nares/inferior nose.
5	Partial rhinectomy, medial maxillectomy	SCC	NEGATIVE L cheek (−) L upper lip (−) L columella (−) L nasal mucosal (−)	34	Discussion of 4 perpendicular margin sites using 3D mapped specimen. Displayed 2D H&E image of L cheek margin and discussed no further need for re‐excision.	NEGATIVE Closest margin: anterior, 4 mm
6	Frontal scalp resection	Pleomorphic dermal sarcoma	NEGATIVE R medial (−) L lateral (−) Anterior (−) Posterior (−)	36	Discussion of tumor biopsy. Discussion of 4 perpendicular margin sites using 3D mapped specimen. Displayed 2D H&E image of L lateral margin, which had evidence of actinic changes.	NEGATIVE All resection margins negative for sarcoma.
7	Wide local excision of preauricular lesion	Atypical fibroxanthoma	NEGATIVE Anterior ear (−) Helical root (−) Ear canal (−) Preauricular deep (−)	32	Discussion of tumor biopsy. Discussion of 4 perpendicular margin sites using 3D mapped specimen. Displayed 2D H&E image of helical root margin, which was negative for malignancy and had evidence of solar elastoses.	NEGATIVE All resection margins negative for malignancy.
8	Subtotal glossectomy	SCC	NEGATIVE Lateral (−) Posterior (−)	31	Discussion of tumor biopsy. Discussion of 2 perpendicular margin sites using 3D mapped specimen. Displayed 2D H&E image of lateral margin, which was negative for malignancy.	NEGATIVE Closest margin: lateral, 4 mm

Abbreviations: 2D, 2‐dimensional; 3D, 3‐dimensional; AR, augmented reality; H&E, hematoxylin and eosin; L, left, R, right; SCC, squamous cell carcinoma.