Table 2.

New COVID-COMBI score for the risk stratification of severe course in patients hospitalized for COVID-19. For score calculation, all points are added up.

Parameter		COVID-COMBI Points
Age (years)	<50	0
	50–59	2
	60–69	4
	70–79	6
	≥80	7
Sex at birth	Female	0
	Male	1
No. of comorbidities a	0	0
	1	1
	≥2	2
SpO2 at room air (%)	≥92	0
	<92	2
GCS	15	0
	<15	2
Urea (mmol/L)	<7	0
	7–14	1
	>14	3
C-reactive protein (mg/L)	<50	0
	50–99	1
	≥100	2
Respiratory rate (breaths/min)	<22	0
	22–29	1
	30–33	2.5
	≥34	3
SpO2/FiO2 ratio	>200	0
	101–200	2
	≤100	3.5
Lactate dehydrogenase (U/L)	≤200	0
	201–299	1
	300–399	2
	400–499	2.5
	≥500	4
Neutrophil–lymphocyte ratio	<4	0
	4–7.9	1
	8–13.9	2
	≥14	2.5

^a The number of comorbidities out of chronic cardiac disease, chronic respiratory disease (excluding asthma), chronic renal disease (estimated glomerular filtration rate ≤30), mild to severe liver disease, dementia, chronic neurological conditions, connective tissue disease, diabetes mellitus (diet-, tablet-, or insulin-controlled), HIV or AIDS, and malignancy. Abbreviations: SpO₂: peripheral oxygen saturation. GCS: Glasgow Coma Scale. FiO₂: fraction of inspired oxygen.