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. 2024 Jul 31;12(8):1702. doi: 10.3390/biomedicines12081702

Table A4.

4C mortality score for COVID-19 [24]. All points are added up.

Parameter 4C Points
Age (years) <50 0
50–59 2
60–69 4
70–79 6
≥80 7
Sex at birth Female 0
Male 1
Number of comorbidities a 0 0
1 1
≥2 2
Respiratory rate (brpm) <20 0
20–29 1
≥ 30 2
Peripheral oxygen saturation ≥92 0
on room air (%) <92 2
GCS 15 0
<15 2
BUN (mg/dL)/urea (mmol/L) <19.6/<7 0
≥19.6–39.2/7–14 1
>39.2/>14 3
C-reactive protein (mg/L) <50 mg/L 0
50–99 1
≥100 2

a The number of comorbidities out of chronic cardiac disease, chronic respiratory disease (excluding asthma), chronic renal disease (estimated glomerular filtration rate ≤30), mild to severe liver disease, dementia, chronic neurological conditions, connective tissue disease, diabetes mellitus (diet-, tablet-, or insulin-controlled), HIV or AIDS, and malignancy. Abbreviations: brpm: breaths per minute. GCS: Glasgow Coma Scale. BUN: blood urea nitrogen.