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. 2024 Aug 27;24:870. doi: 10.1186/s12879-024-09787-y

Table 7.

Non-adherence of patients/care giver to antibiotic prescription at Day 0 in intervention and control arms

Characteristic Overall Intervention arm Control arm Risk difference p-value
n/N (%) 95% CI n/N (%) 95% CI n/N (%) 95% CI % [95% CI]
All 119/1052 (11.3) [9.5, 13.4] 42/536 (7.8) [5.8, 10.4] 77/516 (14.9) [12.1, 18.3] -7.1 [-10.9, -3.3] < 0.001
Age group
 < 5 years 76/625 (12.2) [9.8, 15.0] 26/321 (8.1) [5.6, 11.6] 50/304 (16.4) [12.7, 21.1] -8.3 [-13.5, -3.2] 0.001
 5 to < 10 years 24/260 (9.2) [6.3, 13.4] 12/133 (9.0) [5.2, 15.1] 12/127 (9.4) [5.5, 15.8] -0.4% [-7.5, 6.6] 0.906
 10 to < 18 years 10/106 (9.4) [5.2, 16.5] 4/51 (7.8) [3.1, 18.5] 6/55 (10.9) [5.1, 21.8] -3.1 [-14.1, 8.0] 0.587
 > 18 years 9/61 (14.8) [8.0, 25.7] 0/31 (0.0) [0.0, 11.0] 9/30 (30.0) [16.7, 47.9] -30.0 [-46.4, -13.6] < 0.001
COVID-19 vaccination status
 Fully vaccinated 7/50 (14.0) [7.0, 26.2] 0/25 (0.0) [0.0, 13.3] 7/25 (28.0) [14.3, 47.6] -28.0 [-45.6, -10.4] 0.002
 Partially vaccinated 1/22 (4.5) [0.8, 21.8] 0/14 (0.0) [0.0, 21.5] 1/8 (12.5) [2.2, 47.1] -12.5 [-35.4, 10.4] 0.285
 Not vaccinated 111/975 (11.4) [9.5, 13.5] 42/497 (8.5) [6.3, 11.2] 69/478 (14.4) [11.6, 17.9] -6.0 [-10.0, -2.0] 0.003
 Unknown status 0/5 (0.0) [0.0, 43.4] - - 0/5 (0.0) [0.0, 43.4] - -
Diagnosis
 Respiratory diagnosis 79/397 (19.9) [16.3, 24.1] 26/184 (14.1) [9.8, 19.9] 53/213 (24.9) [19.6, 31.1] -10.8 [-18.4, -3.1] 0.006
 Non-respiratory diagnosis 40/655 (6.1) [4.5, 8.2] 16/352 (4.5) [12.8, 7.3] 24/303 (7.9) [5.4, 11.5] -3.4 [-7.1, 0.4] 0.077
Malaria test result
 Malaria test negative 83/498 (16.7) [13.7, 20.2] 27/253 (10.7) [7.4, 15.1] 56/245 (22.9) [10.0, 28.5] -12.2 [-18.7, -5.7] < 0.001
 Malaria test positive 36/553 (6.5) [4.7, 8.9] 15/283 (5.3) [3.2, 8.6] 21/270 (7.8) [5.1, 11.6] -2.5 [-6.6, 1.6] 0.239