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. 2024 Aug 27;24:584. doi: 10.1186/s12888-024-06022-5

Table 2.

Demographic characteristics per clozapine patients and per treatment periods

Per Patients

All Patients

n = 1,916

Patients who have treatment periods with identified start-datesa

n = 1,391

Patients who have treatment periods with undetermined start-datesa

n = 790

Gender
 Male (%) 1,257 (65.6%) 898 (64.6%) 541 (68.5%)
 Female (%) 659 (34.4%) 493 (35.4%) 249 (31.5%)
Ethnicity
 White (%) 868 (45.3%) 591 (42.5%) 393 (49.7%)
 Black (%) 799 (41.7%) 616 (44.3%) 306 (38.7%)
 Asian (%) 150 (7.8%) 111 (8.0%) 55 (7.0%)
 Other and unknown (%) 99 (5.2%) 73 (5.3%) 36 (4.6%)
Age at clozapine treatment
 Age at first period, mean (SD) - 38.7 (12.7) -
 Age at first known period, mean (SD) 39.0 (12.1) - 39.8 (10.8)
Per Clozapine Treatment Period

All treatment periods

n = 2,787

treatment periods with identified start-dates

n = 1,902

treatment periods with undetermined start-dates

n = 885

Gender
 Male (%) 1,821 (65.3%) 1,213 (63.8%) 608 (68.7%)
 Female (%) 966 (34.6%) 689 (36.2%) 277 (31.3%)
Ethnicity
 White (%) 1,209 (43.4%) 782 (41.1%) 427 (48.2%)
 Black (%) 1,220 (43.8%) 872 (45.8%) 348 (28.0%)
 Asian (%) 219 (7.9%) 154 (8.1%) 65 (7.3%)
 Other and unknown (%) 139 (5%) 94 (4.9%) 45 (5.1%)
Age at clozapine treatment periods
 Age range at start of period 12–88 12–88 12–76
 Periods starting at ages 0–19 (%)b 66 (2.4%) 50 (2.6%) 16 (1.8%)
 Periods starting at ages 20–39 (%)b 1,432 (51.4%) 1,007 (52.9%) 425 (48.0%)
 Periods starting at ages 40–59 (%)b 1,126 (40.4%) 722 (38.0%) 404 (45.6%)
 Periods starting at age 60 and over (%)b 163 (5.8%) 123 (6.5%) 40 (4.5%)
Duration of clozapine treatment periods
 Average duration, years 4.5 (4.8) 3.1 (3.7) -
 Median duration (Interquartile range), years 2.2 (7.3) 1.4 (4.4) -
 Shorter than 6 months (%) - 557 (29.3%) -
 Longer than 2 years (%) 1,437 (51.6%) 815 (42.8%) 622 (70.3%)

aPatients can have both periods with identified start-date, and (additional) periods with undetermined start-date, therefore can appear in both columns

bThe age stratification was done per treatment period, meaning that the same patient can contribute to more than one category of age, per the age in which the treatment period was started