Table 4.
Validation of algorithm results
| # | % confirmed | |
|---|---|---|
| Excluded clozapine treatment periods | ||
| Total number of periods | 425 | |
| Number of periods randomly selected for validation (%) | 90 (21.2%) | |
| Number of confirmed periodsa | 76 | 84.4% |
| Clozapine treatment periods with identified start-date | ||
| Total number of periods | 1,902 | |
| Number of periods randomly selected for validation (%) | 211 (11.1%) | |
| Number of confirmed periods | 210 | 99.5% |
| Start-date accuracyb | ||
| Highly accurate (range of up to 15 days) | 202 | 96.2% |
| Accurate (range of 15–30 days) | 3 | 1.4% |
| Partially accurate (range of 30–60 days) | 2 | 1.0% |
| Inaccurate (range of more than 60 days) | 3 | 1.4% |
| End-date accuracyb | ||
| Highly accurate (range of up to 15 days) | 67 | 71.3% |
| Accurate (range of 15–30 days) | 13 | 13.8% |
| Partially accurate (range of 30–60 days) | 13 | 13.8% |
| Inaccurate (range of more than 60 days) | 1 | 1.1% |
| No end-date to detectc | 116 (55.2%) | |
| Clozapine treatment periods with undetermined start-date | ||
| Total number of periods | 885 | |
| Number of periods randomly selected for validation (%) | 114 (12.9%) | |
| Number of confirmed periods | 114 | 100% |
aConfirmed excluded periods are treatment periods found to be "empty", meaning no clozapine was prescribed or total length of treatment was shorter than 7 days
bValidated for periods with identified start-date only
cEnd-date could not be detected as patients were either transferred outside of SLaM or reached the end of the study observation window