Table 1.
Patient characteristics of the whole cohort according to antidiabetic medication and statin use.
| Metformin | Insulin | Other ADM | Statin | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Yes (%) | No (%) | Yes (%) | No (%) | Yes (%) | No (%) | Yes (%) | No (%) | Total (%) | |
| Total | 885 (100) | 498 (100) | 533 (100) | 850 (100) | 749 (100) | 634 (100) | 529 (100) | 854 (100) | 1383 (100) |
| Sex | |||||||||
| Male | 733 (83) | 376 (76) | 426 (80) | 683 (80) | 598 (80) | 511 (81) | 435 (82) | 674 (79) | 1109 (80) |
| Female | 152 (17) | 122 (24) | 107 (20) | 167 (20) | 151 (20) | 123 (19) | 94 (18) | 180 (21) | 274 (20) |
| Education | |||||||||
| Basic | 275 (31) | 149 (30) | 178 (33) | 246 (29) | 235 (31) | 189 (30) | 168 (32) | 256 (30) | 424 (31) |
| Intermediate | 338 (38) | 207 (42) | 206 (39) | 339 (40) | 281 (38) | 264 (42) | 213 (40) | 332 (39) | 545 (39) |
| Higher | 272 (31) | 142 (29) | 149 (28) | 265 (31) | 233 (31) | 181 (29) | 148 (28) | 266 (31) | 414 (30) |
| Follow-up time (years) | |||||||||
| Median | 0.5 | 0.3 | 0.4 | 0.4 | 0.4 | 0.4 | 0.5 | 0.3 | 0.4 |
| Interquartile range | 0.1–1.5 | 0.04–1.0 | 0.07–1.2 | 0.09–1.3 | 0.08–1.3 | 0.09–1.2 | 0.1–1.4 | 0.06–1.2 | 0.08–1.3 |
| Duration of diabetes (years) | |||||||||
| Median | 9.9 | 9.0 | 13.7 | 7.7 | 10.4 | 8.5 | 11.4 | 8.6 | 9.6 |
| Interquartile range | 6.1–14.9 | 5.1–15.9 | 9.1–18.1 | 4.4–11.7 | 6.9–15.2 | 4.3–15.2 | 7.2–16.7 | 5.0–13.5 | 5.6–15.2 |
| Hepatitis | |||||||||
| Yes | 55 (6) | 48 (10) | 47 (9) | 56 (7) | 50 (7) | 53 (8) | 34 (6) | 69 (8) | 103 (7) |
| No | 830 (94) | 450 (90) | 486 (91) | 794 (93) | 699 (93) | 581 (92) | 495 (94) | 785 (92) | 1280 (93) |
| Cirrhosis | |||||||||
| Yes | 190 (21) | 144 (29) | 152 (29) | 182 (21) | 170 (23) | 164 (26) | 91 (17) | 243 (28) | 334 (24) |
| No | 695 (79) | 354 (71) | 381 (71) | 668 (79) | 579 (77) | 470 (74) | 438 (83) | 611 (72) | 1049 (76) |
| Age at HCC diagnosis (years) | |||||||||
| Median | 71 | 72 | 71 | 72 | 72 | 71 | 72 | 71 | 72 |
| Interquartile range | 66–78 | 65–80 | 65–77 | 66–79 | 66–79 | 65–78 | 67–78 | 65–78 | 66–78 |
| Stage of HCC | |||||||||
| Local | 173 (20) | 119 (24) | 105 (20) | 187 (22) | 167 (22) | 125 (20) | 97 (18) | 195 (23) | 292 (21) |
| Advanced | 228 (26) | 135 (27) | 153 (29) | 210 (25) | 204 (27) | 159 (25) | 122 (23) | 241 (28) | 363 (26) |
| Unknown | 484 (55) | 244 (49) | 275 (52) | 453 (53) | 378 (50) | 350 (55) | 310 (59) | 418 (49) | 728 (53) |
ADM = antidiabetic medication, HCC = hepatocellular carcinoma.