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. 2024 Jul 24;12(8):1654. doi: 10.3390/biomedicines12081654

Table 3.

Characteristics of patients with localized tumors according to antidiabetic medication and statin use.

Metformin Insulin Other ADM Statin
Yes (%) No (%) Yes (%) No (%) Yes (%) No (%) Yes (%) No (%) Total (%)
Total 173 (100) 119 (100) 105 (100) 187 (100) 167 (100) 125 (100) 97 (100) 195 (100) 292 (100)
Sex
Male 143 (83) 92 (77) 79 (75) 156 (83) 139 (83) 96 (77) 78 (80) 157 (81) 235 (80)
Female 30 (17) 27 (23) 26 (25) 31 (17) 28 (17) 29 (23) 19 (20) 38 (19) 57 (20)
Education
Basic 56 (32) 28 (24) 34 (32) 50 (27) 51 (31) 33 (26) 26 (27) 58 (30) 84 (29)
Intermediate 62 (36) 49 (41) 39 (37) 72 (39) 65 (39) 46 (37) 48 (49) 63 (32) 111 (38)
Higher 55 (32) 42 (35) 32 (30) 65 (35) 51 (31) 46 (37) 23 (24) 74 (38) 97 (33)
Follow-up time (years)
Median 0.8 0.6 0.6 0.8 0.8 0.7 0.6 0.7 0.7
Interquartile range 0.1–2.9 0.08–2.4 0.06–2.5 0.2–2.7 0.2–2.9 0.08–2.0 0.1–2.5 0.1–2.8 0.1–2.7
Duration of diabetes (years)
Median 9.6 9.5 12.3 7.8 9.8 8.1 10.2 9.3 9.6
Interquartile range 5.3–13.9 6.0–16.0 8.2–16.9 4.6–12.3 6.8–13.9 3.7–15.8 5.9–15.7 5.3–14.2 5.3–14.9
Hepatitis
Yes 12 (7) 7 (6) 9 (9) 10 (5) 8 (5) 11 (9) 8 (8) 11 (6) 19 (7)
No 161 (93) 112 (94) 96 (91) 177 (95) 159 (95) 114 (91) 89 (92) 184 (94) 273 (93)
Cirrhosis
Yes 41 (24) 31 (26) 29 (28) 43 (23) 43 (26) 29 (23) 22 (23) 50 (26) 72 (25)
No 132 (76) 88 (74) 76 (72) 144 (77) 124 (74) 96 (77) 75 (77) 145 (74) 220 (75)
Age at HCC diagnosis (years)
Median 71 72 70 72 72 70 73 70 71
Interquartile range 65–77 64–80 63–77 65–79 66–79 63–77 66–79 63–78 65–78

ADM = antidiabetic medication, HCC = hepatocellular carcinoma.