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. 2024 Aug 22;12(8):1922. doi: 10.3390/biomedicines12081922

Table 3.

Correlation coefficient (Spearman’s r) and p values for IGF-1 1 and IGFBP-3 2 with vitamin D metabolites in the CRA 3 group and control group.

Entire Patient Group IGF-1 and
IGFBP-3
IGF-1 and
Cholecalciferol
IGF-1 and Calcidiol IGF-1 and
Calcitriol
IGF-1 and Age IGF-1 and
BMI 4
Spearman’s r coefficient 0.25 −0.23 0.05 −0.31 −0.40 −0.05
p 0.01 0.03 0.63 0.003 0.0001 0.61
Entire patient group IGFBP-3 and cholecalciferol IGFBP-3 and calcidiol IGFBP-3 and calcitriol IGFBP-3 and age IGFBP-3 and BMI
Spearman’s r coefficient −0.07 0.01 −0.09 −0.20 0.06
p 0.50 0.92 0.36 0.06 0.53
CRA group IGF-1 and
IGFBP-3
IGF-1 and cholecalciferol IGF-1 and calcidiol IGF-1 and calcitriol IGF-1 and age IGF-1 and BMI
Spearman’s r coefficient −0.66 −0.24 −0.12 −0.34 −0.39 0.05
p <0.0001 0.07 0.37 0.01 0.003 0.70
CRA group IGFBP-3 and cholecalciferol IGFBP-3 and calcidiol IGFBP-3 and calcitriol IGFBP-3 and age IGFBP-3 and BMI
Spearman’s r coefficient 0.10 0.01 0.22 0.15 0.19
p 0.46 0.94 0.10 0.25 0.15
Control group IGF-1
and
IGFBP-3
IGF-1 and cholecalciferol IGF-1 and calcidiol IGF-1 and calcitriol IGF-1 and age IGF-1 and BMI
Spearman’s r coefficient 0.16 −0.22 0.28 −0.28 −0.45 −0.29
p 0.36 0.22 0.11 0.10 0.01 0.10
Control group IGFBP-3 and cholecalciferol IGFBP-3 and calcidiol IGFBP-3 and calcitriol IGFBP-3 and age IGFBP-3 and BMI
Spearman’s r coefficient −0.11 −0.11 −0.23 −0.05 −0.31
p 0.52 0.52 0.19 0.76 0.07

1 IGF-1—insulin-like growth factor-1; 2 IGFBP-3—insulin-like growth factor binding protein-3; 3 CRA—colorectal adenoma, 4 BMI—body mass index.