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Effect of islet TNF-α release on early apoptosis (▼, dashed line, left y-axis) and glucose stimulation index (●, solid line, right y-axis). Each data point represents the intensity of Annexin-V staining or the glucose stimulation index in relation to the corresponding generation of TNF-α secretion. The correlation coefficient (r) was calculated using Spearman’s rank correlation after outlier identification (n = 32).
