Table 1.
Clinicopathological characteristics of gastric carcinoma patients accordingly with histopathological subtype.
| Total GC (n = 29) | Diffuse/Poorly Cohesive GC * (n = 13) (45%) | Intestinal-Subtype GC ** (n = 16) (55%) |
p Value a | |
|---|---|---|---|---|
| Gender, n (%) | ||||
| Male | 13/29 | 6/13 (46%) | 7/16 (43%) | 0.90 (NS) |
| Female | 16/29 | 7/13 (54%) | 9/16 (56%) | |
| Age (years, median) | 63 ± 17 | 57 (27–71) | 75 (59–82) | 0.0004 b |
| Smoking | ||||
| Negative | 12/22 | 4/12 | 8/12 | 0.77 (NS) |
| Positive | 10/22 | 3/10 | 7/10 | |
| Tumor size (mm), n (%) | ||||
| <50 | 10/27 | 4/11 (36%) | 6/16 (37%) | 0.10 (NS) b |
| ≥50 | 17/27 | 7/11 (64%) | 10/16 (63%) | 0.95 (NS) |
| Depth tumor invasion (T) | ||||
| T1–T2 | 6/29 | 2/13 (15%) | 4/16 (33%) | 0.5 (NS) |
| T3–T4 | 23/29 | 11/13 (85%) | 12/16 (67%) | |
| Lymphatic invasion (N) | ||||
| Negative | 11/28 | 1/13 (7%) | 10/15 (67%) | 0.0014 |
| Positive | 17/28 | 12/13 (92%) | 5/15 (33%) | |
| Metastasis (M), n (%) | ||||
| Negative | 24/29 | 9/13 (69%) | 15/16 (94%) | 0.14 (NS) |
| Positive | 5/29 | 4/13 (31%) | 1/16 (6%) | |
| TNM status | ||||
| I–II | 16/29 | 5/13 (38.5%) | 11/16 (69%) | 0.10 (NS) |
| III–IV | 13/29 | 8/13 (61.5%) | 5/16 (31%) | |
| Vascular invasion, n + (%) | ||||
| Negative | 9/29 | 3/13 (23%) | 6/16 (38%) | 0.67 (NS) |
| Positive | 20/29 | 10/13 (77%) | 10/16 (62%) | |
| Neural invasion, n (%) | ||||
| Negative | 23/29 | 2/13 (15%) | 4/16 (25%) | 0.66 (NS) |
| Positive | 6/29 | 11/13 (68%) | 12/16 (75%) |
* poorly cohesive adenocarcinoma/diffuse-type carcinoma; ** intestinal-type adenocarcinoma. a, Chi-square test, Yates’ continuity corrected chi-square test, or Fisher’s exact test if appropriate; b, Mann–Whitney. NS = not statistically different. The characteristics of the patients included in the cohort were already reported in ref. [29].