Table 1.

Weights, BP, and plasma creatinine level.

Groups	CN	AD	CNCS	ADCS		p Value
					AD	CS	AD × CS
Body weight (BW) (g)	415 ± 18	415 ± 14	351 ± 7 *#	426 ± 9	0.007	0.046	0.007
Left kidney weight (LKW) (g)	1.83 ± 0.08	1.94 ± 0.07	1.71 ± 0.06 #	1.97 ± 0.08	0.014	NS	NS
Combined kidney weight (CKW) (g)	3.68 ± 0.16	3.94 ± 0.13	3.41 ± 0.1 #	4.02 ± 0.13	0.003	NS	NS
LKW-to-BW ratio (g/kg)	0.44 ± 0.01	0.47 ± 0.01	0.49 ± 0.01	0.47 ± 0.03	NS	NS	NS
CKW-to-BW ratio (g/kg)	0.89 ± 0.01	0.95 ± 0.02	0.97 ± 0.02	0.95 ± 0.05	NS	NS	NS
Systolic BP (mmHg)	133 ± 1	149 ± 2 *	135 ± 1 #	137 ± 1 #	<0.001	<0.001	<0.001
Diastolic BP (mmHg)	88 ± 1	91 ± 3	88 ± 2	89 ± 2	NS	NS	NS
Creatinine (μM)	16.5 ± 0.5	18.8 ± 0.8	16.2 ± 0.8	18.8 ± 0.7	0.002	NS	NS

N = 8/group; BP = blood pressure. CN = standard diet; AD = standard diet containing 0.5% adenine; CNCS = standard diet containing 3% chondroitin sulfate; ADCS = standard diet containing 0.5% adenine plus 3% CS; AD × CS = interaction of AD × CS; NS = not significant. * p < 0.05 vs. CN; # p < 0.05 vs. AD.