Table 2.
Groups | CN | AD | CNCS | ADCS | p Value | ||
---|---|---|---|---|---|---|---|
AD | CS | AD × CS | |||||
L-citrulline (μM) | 54.3 ± 3.3 | 43.0 ± 2.5 | 48.0 ± 1.7 | 46.1 ± 3.2 | 0.024 | NS | NS |
L-arginine (μM) | 392.5 ± 21.6 | 286.2 ± 11.8 | 365.9 ± 18.2 | 302.1 ± 16.3 | <0.001 | NS | NS |
ADMA (μM) | 2.06 ± 0.1 | 2.19 ± 0.1 | 1.88 ± 0.06 | 2.05 ± 0.17 | NS | NS | NS |
SDMA (μM) | 2.07 ± 0.16 | 2.49 ± 0.20 | 2.28 ± 0.10 | 2.02 ± 0.08 | NS | NS | 0.035 |
AAR (μM/μM) | 192.9 ± 12.2 | 132.5 ± 7.9 | 197.1 ± 13.0 | 152.7 ± 11.8 | <0.001 | 0.044 | NS |
N = 8/group; AAR = L-arginine-to-ADMA ratio; CN = standard diet; AD = standard diet containing 0.5% adenine; CNCS = standard diet containing 3% chondroitin sulfate; ADCS = standard diet containing 0.5% adenine plus 3% CS; AD × CS = interaction of AD × CS; NS = not significant.