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. 2024 Aug 19;16(16):2881. doi: 10.3390/cancers16162881

Figure 2.

Figure 2

The volcano plot displays the relationship between the magnitude of gene expression change (log2 of fold change on the x-axis) and the statistical significance of this change (−log10 of false discovery rate (FDR) on the y-axis). Red points represent significant DEGs identified when comparing C1 vs C2 using an FDR < 0.05 (horizontal dashed line) after post-hoc filtering performed on |log2(FC)| > 0.58 (vertical dashed lines). DEGs downregulated in C1 correspond to DEGs upregulated in C2.