Table 4.
Key nodes of the backbone network that showed varied levels from statistical analysis. Pure bottleneck proteins are evidenced by an asterisk.
| Gene | Closeness Centrality | Degree | Betweenness Centrality | Protein |
|---|---|---|---|---|
| COPB2 * | 0.36 | 6 | 0.002 | Beta-COP |
| DPP4 * | 0.37 | 5 | 0.0001 | ADABP |
| EEF2 | 0.52 | 44 | 0.022 | EF-2 |
| FN1 | 0.51 | 37 | 0.025 | FN |
| GOT1 * | 0.32 | 5 | 0.0002 | cAspAT |
| IGHV3–43D * | 0.31 | 2 | 0.0001 | Immunoglobulin heavy variable 3–43D |
| LGALS3 * | 0.43 | 12 | 0.004 | Gal-3 |
| LTF * | 0.38 | 10 | 0.003 | Lactotransferrin |
| PDHB * | 0.41 | 9 | 0.0003 | PDHE1-B |
| WASL * | 0.41 | 14 | 0.003 | N-WASP |
| WDR5 * | 0.41 | 9 | 0.002 | WD repeat-containing protein 5 |