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. 2024 Aug 22;16(16):2922. doi: 10.3390/cancers16162922

Table 2.

Logistic regression models.

Univariable Multivariable
Variables (Categories) Odds Ratios [95% Conf Interval] Adjusted Odds Ratios [95% Conf Interval]
Sex AUC = 0.52 AUC = 0.84
Male [Ref] [Ref]
Female 1.19 1.03 1.37 0.96 0.81 1.13
Age AUC = 0.41
≤25 [Ref] [Ref]
26–50 0.91 0.75 1.10 0.78 0.62 0.98
51–75 0.56 0.46 0.68 0.68 0.54 0.87
≥76 0.29 0.20 0.42 0.54 0.35 0.85
Race AUC = 0.52
Non-Hispanic White [Ref] [Ref]
Non-Hispanic Black 1.61 1.29 2.01 1.23 0.95 1.60
Hispanic 0.99 0.73 1.35 0.76 0.54 1.09
Asian/Pacific Islander 1.03 0.62 1.70 1.29 0.71 2.32
Other 0.81 0.42 1.54 0.62 0.31 1.26
Charlson–Deyo Score AUC = 0.48
0–1 [Ref] [Ref]
≥2 0.44 0.31 0.63 0.74 0.49 1.12
Insurance status AUC = 0.56
Not insured 0.96 0.66 1.38 0.91 0.59 1.40
Medicaid/Medicare/OG 0.54 0.46 0.63 0.78 0.64 0.95
Private [Ref] [Ref]
Unknown 0.42 0.20 0.88 0.39 0.17 0.88
Tumor differentiation AUC = 0.56
Well differentiated [Ref] [Ref]
Moderately differentiated 2.07 1.67 2.61 1.25 0.96 1.64
Unknown 1.74 1.44 2.11 1.13 0.90 1.43
LVI  AUC = 0.70
Lymph vascular (−) [Ref] [Ref]
Lymph vascular (+) 7.43 6.23 8.86 4.09 3.37 4.97
Unknown 3.48 2.92 4.16 2.42 1.95 3.01
Tumor depth  AUC = 0.55
Confined to the appendiceal wall [Ref] [Ref]
Invading the subserosa and beyond 1.01 0.82 1.23 1.07 0.84 1.37
Unknown 0.68 0.57 0.81 0.79 0.64 0.97
Tumor size  AUC = 0.79
<1 cm [Ref] [Ref]
≥1 cm but <2 cm 6.21 4.81 8.01 4.16 3.18 5.43
≥2 cm 21.45 16.91 27.22 14.43 11.27 18.49
Surgical margins AUC = 0.53
Negative margins [Ref] [Ref]
Positive margins 4.21 2.96 5.98 2.52 1.67 3.89
Unknown margins 2.26 1.39 3.67 2.32 1.29 4.20
All patients were included in the model (n = 5353).