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. 2024 Aug 24;19:1905–1920. doi: 10.2147/COPD.S468825

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© 2024 Liu et al.

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Effects of ECC-BYF III on lung function and lung histopathology in COPD rats. (A) Establishment process and treatment measures of COPD rat model induced by smoking and Klebsiella pneumoniae. (B–F) Tidal volume, peak expiratory flow, forced vital capacity, forced expiratory volume at 0.1s and Cdyn of rats. (G) H and E pathological section of lung (200×). (H–J) Mean alveolar number, mean alveolar intercept, and bronchial wall thickness. All data are represented as mean ± SD (n=6~8). *P < 0.05 and **P < 0.01 as compared to Normal group, ^#P < 0.05 and ^##P < 0.01 as compared to Model group.