Table 2.

Prevalence, histology, and location of lung cancer in patients with ILDs, based on refs. [45,52,59,62,76,77].

ILD	Prevalence of LC	Most Common LC Histology	Location
IPF	Median 11.6% in European cohorts and 15.3% in Asian cohorts	Squamous cell carcinoma	Lower lobes, fibrotic areas
CTD-ILD	1.9–9%	Adenocarcinoma	Peripheral lung lesions, equal distribution in upper and lower lobes
Hypersensitivity pneumonitis	0–10.6%	Squamous cell carcinoma	Peripheral lung lesions, equal distribution in upper and lower lobes

LC: lung cancer; IPF: idiopathic pulmonary fibrosis; CTD-ILD: connective tissue disease-associated ILD.