ABHD17A |
α/β-hydrolase Domain Containing 17A |
AID |
associated autoinflammatory disease |
AS |
Alternative splicing |
ASC |
Apoptosis-associated Speck-like protein containing a CARD |
ATP |
Adenosine TriPhosphate |
BIR |
Baculoviral Inhibitory Repeat |
CAPS |
Cryopyrin-Associated Periodic Syndrome |
CARD |
Caspase Recruitment Domain |
Cbl-b |
Casitas B-lineage Lymphoma-b |
CCDC50 |
Coiled-Coil Domain Containing 50 |
CIAS1 |
Cold-Induced Autoinflammatory Syndrome 1 |
CINCA |
Chronic Infantile Neurological Cutaneous and Articular syndrome |
CLR |
C-type Lectin Receptor |
Cryo-EM |
Cryo-electronic microscopy |
CSNK1A1 |
Casein Kinase 1, Alpha 1 |
DAMP |
Danger-Associated Molecular Pattern |
dsRNA |
double-strand RNA |
GSDMD |
Gasdermin-D |
H2O2
|
Hydrogen peroxide |
HSC70 |
Heat Shock Cognate 70 |
HSP90 |
Heat Shock Protein 90 |
IL-1β |
Interleukin 1β |
IL-18 |
Interleukin 18 |
K+ |
Potassium ion |
LPS |
Lipopolysaccharide |
LRR |
Leucine-Rich Repeat |
MARCH7 |
Membrane-Associated RING-CH type finger protein 7 |
MSU |
crystals of monosodium urate |
MTS |
Mitochondrial Targeting Sequence |
MyD88 |
Myeloid differentiation primary response 88 |
NACHT |
Nucleotide-binding and oligomerization domain |
NALP |
NACHT, LRR, and PYD domains-containing protein |
NEK7 |
NIMA-related kinase 7 |
NF-kB |
Nuclear Factor kappa-light-chain-enhancer of activated B cells |
NLR |
NOD-Like Receptor |
NLRP3 |
NOD-like receptor family, pyrin domain containing 3 |
NOMID |
Neonatal Onset Multisystem Inflammatory Disease |
PAMP |
Pathogen-Associated Molecular Pattern |
PI4P |
phosphatidylinositol 4-phosphate |
PRR |
Pathogen-Recognition Receptor |
PTM |
Post-Translational Modification |
PTPN22 |
Protein Tyrosine Phosphatase, Non-Receptor Type 22 |
PYD |
Pyrin domain |
RNAseq |
Ribonucleic Acid sequencing |
RNF125 |
Ring Finger Protein 125 |
ROS |
Reactive Oxygen Species |
RLR |
RIG-I-Like Receptor |
SiO2
|
Silica |
SGT1 |
Suppressor of G2 allele of SKP1 |
SQSTM1 |
Sequestosome 1 |
TLR |
Toll-Like Receptor |
TRIF |
TIR-domain-containing adapter-inducing interferon-β |
ZDHHC12 |
Zinc Finger DHHC-Type Containing 12 |