Table 7.

Multivariate analysis for disease-free survival.

		p-Value	HR	95.0% CI
				Inferior	Superior
Phase 1	Ki67	0.037	1.216	1.012	1.461
	margin (1 vs. 0) *	0.036	2.501	1.060	5.904
	localization	0.233	0.530	0.187	1.504
	previous surgery	0.321	1.489	0.678	3.270
	CCI	0.008	1.526	1.119	2.079
	type of surgery (other)	0.556	0.681	0.189	2.447
	type of Surgery (en bloc resection)	0.868	0.913	0.313	2.664
Phase 2	Ki67	0.033	1.216	1.016	1.455
	margin (1 vs. 0) *	0.026	2.598	1.119	6.032
	localization	0.210	0.548	0.214	1.403
	previous surgery	0.279	1.529	0.709	3.298
	CCI	0.004	1.513	1.141	2.007
Phase 3	Ki67	0.032	1.216	1.017	1.453
	margin (1 vs. 0) *	0.018	2.771	1.195	6.429
	localization	0.203	0.547	0.216	1.383
	CCI	0.004	1.517	1.143	2.013
Phase 4	Ki67	0.061	1.188	0.992	1.421
	margin (1 vs. 0) *	0.019	2.667	1.173	6.059
	CCI	0.004	1.502	1.142	1.976

* 0 = adequate margin; 1 = inadequate margin. Statistically significant p values are shown in red color.