Table 1.
Characteristics of participants with PAD according to baseline six-minute walk distance.
| Total (n = 369) 21–701 m |
Tertile 1 (n = 123) 21–326 m |
Tertile 2 (n = 124) 327–412 m |
Tertile 3 (n = 122) 412–701 m |
Trend p-value |
|
|---|---|---|---|---|---|
| Age, years | 69.4 (10.0) | 71.96 (10.1) | 69.44 (9.9) | 66.70 (9.4) | < 0.0001 |
| Female | 114 (30.9) | 45 (36.6) | 40 (32.3) | 29 (23.8) | 0.0300 |
| African American | 111 (30.1) | 41 (33.3) | 39 (31.5) | 31 (25.4) | 0.18 |
| ABI | 0.67 (0.17) | 0.59 (0.17) | 0.69 (0.17) | 0.74 (0.15) | < 0.0001 |
| BMI, kg/m2 | 29.7 (6.1) | 31.12 (6.8) | 29.61 (6.1) | 28.22 (5.0) | 0.0002 |
| Smoker: current or former | 329 (89.2) | 109 (88.6) | 111 (89.5) | 109 (89.3) | 0.85 |
| Hypertension | 334 (90.5) | 118 (95.9) | 114 (91.9) | 102 (83.6) | 0.001 |
| Diabetes | 150 (40.7) | 65 (52.9) | 49 (39.5) | 36 (29.5) | < 0.001 |
| Angina | 88 (23.8) | 35 (28.5) | 32 (25.8) | 21 (17.2) | 0.039 |
| Myocardial infarction | 74 (20.1) | 27 (22.0) | 24 (19.4) | 23 (18.9) | 0.54 |
| Heart failure | 45 (12.2) | 28 (22.8) | 13 (10.5) | 4 (3.3) | < 0.0001 |
| Stroke | 60 (16.3) | 27 (22.0) | 20 (16.1) | 13 (10.7) | 0.017 |
| Pulmonary disease | 139 (37.7) | 59 (48.0) | 46 (37.1) | 34 (27.9) | 0.001 |
| Cancer | 54 (14.6) | 18 (14.6) | 18 (14.5) | 18 (14.8) | 0.98 |
| LDL, mg/dL | 91.7 (32.3) | 89.70 (33.3) | 91.11 (32.5) | 94.37 (31.2) | 0.26 |
| HDL, mg/dL | 49.4 (16.4) | 47.40 (14.6) | 50.08 (19.9) | 50.85 (14.1) | 0.10 |
| Statin use | 271 (73.4) | 90 (73.2) | 98 (79.0) | 83 (68.0) | 0.36 |
| Six-minute walk distance, m | 359.3 (122.9) | 221.84 (81.7) | 372.41 (22.9) | 484.53 (59.1) | < 0.0001 |
| Reported blocks walked in the past week | 26.8 (56.1) | 9.60 (14.7) | 19.79 (42.9) | 51.48 (80.9) | < 0.0001 |
For continuous variables, data are in the form: mean (SD); for categorical variables: n (%).
ABI, ankle-brachial index; BMI, body mass index; HDL, high density lipoprotein; LDL, low density lipoprotein, PAD, peripheral artery disease.