Table 4.
Association of WIQ speed score with lower extremity events, with and without adjustment for ABI.
| Tertile 1 HR (95% CI) (0.0–22.8) n = 113 |
Pairwise p-value relative to 3rd tertile | Tertile 2 HR (95% CI) (25.0–46.7) n = 122 |
Pairwise p-value relative to 3rd tertile | Tertile 3 HR (95% CI) (50.0–100) n = 114 |
|
|---|---|---|---|---|---|
| Model 1 | |||||
| All lower extremity outcomes | 1.62 (1.11, 2.37) n = 64 |
0.0122 | 0.94 (0.63, 1.39) n = 54 |
0.75 | Ref. n = 51 |
| Model 2 | |||||
| All lower extremity outcomes | 1.80 (1.20, 2.69) |
0.0041 | 0.98 (0.66, 1.46) |
0.93 | Ref. |
| Model 1 | |||||
| Lower extremity revascularization | 2.17 (1.05, 4.49) n = 21 |
0.0366 | 2.00 (0.98, 4.05) n = 23 |
0.06 | Ref. n = 12 |
| Model 2 | |||||
| Lower extremity revascularization | 2.22 (1.04, 4.71) |
0.0390 | 2.01 (0.99, 4.10) |
0.055 | Ref. |
| Model 1 | |||||
| ABI decline > 15%a | 1.56 (1.02, 2.39) n = 51 |
0.0410 | 0.82 (0.52, 1.29) n = 39 |
0.39 | Ref. n = 40 |
| Model 2 | |||||
| ABI decline > 15%a | 1.88 (1.19, 2.98) |
0.0070 | 0.90 (0.57, 1.42) |
0.64 | Ref. |
| Model 1 | |||||
| Critical limb ischemia or amputation | 3.48 (0.69, 17.51) n = 7 |
0.13 | 1.54 (0.24, 9.68) n = 3 |
0.65 | Ref. n = 2 |
| Model 2 | |||||
| Critical limb ischemia or amputation | 3.10 (0.58, 16.64) |
0.19 | 1.48 (0.23, 9.39) |
0.68 | Ref. |
Model 1 adjusteding for age, sex, race, BMI, smoking, comorbidities, and statin use. Model 2 adjusted for variables in Model 1 + ABI.
a
Three people are not included in the analyses for ABI decline > 15%: two in tertile 2, and one in tertile 3.
ABI, ankle–brachial index; BMI, body mass index; HR, hazard ratio; WIQ, Walking Impairment Questionnaire.