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The multifaced expression and role of tissue factor (TF). In the context of the crossroad between coagulation cascade and signal transduction, the various cellular sources of TF (on the left), the different isoforms—encrypted and decrypted—(in the middle), and the alternatively spliced forms (soluble and asTF) are shown. Created with BioRender.com. asTF, alternatively spliced tissue factor; EVs, extracellular vesicles; TF, tissue factor.
