Figure 3.

Mitochondrial mass and biogenesis markers in the livers of wild-type and ob/ob mice. (A) Bar charts showing the semiquantitative optical density (arbitrary units of blot bands) of porin normalized to β-actin. (B) mRNA expression of mitochondrial transcription factor A (TFAM), an indicator of mitochondrial biogenesis. The data are expressed as the means ± SDs that were calculated from at least three separate measurements. WC—untreated wild-type; WM—wild-type plus melatonin; ObC—untreated ob/ob; ObM—ob/ob plus melatonin. Statistical comparisons: # wild-type vs. ob/ob and * treated with melatonin vs. untreated counterpart. The number of symbols indicates the level of statistical significance: * for p < 0.050, ** for p < 0.010, and ### for p < 0.001.