Figure 7.

Markers of mitochondrial dynamics in the livers of wild-type and ob/ob mice. Bar charts showing the semiquantitative densitometric analysis (arbitrary units of blot bands) of Western blots for mitofusin 2 (MFN2) and dynamin-related protein 1 (DRP1) normalized to β-actin. Representative immunoblot images and the MFN2/DRP1 ratio are also shown. The data are expressed as the means ± SDs that were calculated from at least three separate measurements. WC—untreated wild-type; WM—wild-type plus melatonin; ObC—untreated ob/ob; ObM—ob/ob plus melatonin. Statistical comparisons: # wild-type vs. ob/ob and * treated with melatonin vs. untreated counterpart. The number of symbols indicates the level of statistical significance: */# for p < 0.050, and ***/### for p < 0.001.