Table 1.

Represents the current understanding of the adrenoreceptors distribution and their respective NE affinity. (++ represents areas where the concentration is particularly high) (based on [63,64,65].

RECEPTOR	REGIONS FOUND	NE Affinity
α 1 A, B, D	LC, olfactory bulb, cerebral cortex, dentate gyrus, amygdala, thalamus	Intermediate
α 2 A, B, C, D	Pre- and post-synaptically at LC, Amygdala, hypothalamus, spinal cord	High
β 1	Cerebral cortex (astrocytes ++), spinal cord	Low
β 2	Cerebral cortex, cerebellum (astrocytes ++)	Low
β 3	Hippocampus (astrocytes ++)	Low