Figure 2.

Activation of the 5-HT1A receptor ameliorates NMJ synaptic transmission of the dfmr1^Δ50 larvae. Representative traces of spontaneous (A) and evoked (B) activity in larvae from the control, dfmr1^Δ50, the control treated with eltoprazine, and dfmr1^Δ50 treated with eltoprazine. (C) Quantification of spontaneous event frequency (Hz) (left) and amplitude (mV) (right). Each dot represents the measurement of a single NMJ. (D) Quantification of evoked EJP amplitude (mV). n ≥ 7 larvae for each condition. All the data are presented as dot plots, and error bars show the standard error of the mean. 2-way ANOVA, multiple comparisons: * p < 0.05, ** p < 0.01, *** p < 0.001, n.s. means no significant.