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. 2024 Aug 9;25(16):8694. doi: 10.3390/ijms25168694

Table 3.

Correlation of immunoregulatory cells and cytokines with different rheumatoid arthritis disease activity scores.

Items DAS28-ESR DAS28-CRP SDAI DAS28-MCP-1
Breg rho −0.043 −0.034 −0.075 −0.117
p 0.605 0.681 0.366 0.158
Tr1 rho −0.047 −0.014 −0.024 −0.094
p 0.577 0.867 0.771 0.258
M2 rho 0.112 0.097 0.089 0.144
macrophages p 0.178 0.246 0.283 0.081
IL-4 rho 0.103 0.123 0.126 0.139
p 0.215 0.139 0.130 0.094
IL-5 rho 0.169 0.137 0.154 0.135
p 0.042 0.099 0.063 0.104
IL-9 rho 0.097 0.100 0.055 0.098
p 0.245 0.230 0.509 0.237
IL-10 rho −0.060 −0.040 −0.047 −0.137
p 0.471 0.628 0.572 0.099
IL-13 rho 0.125 0.127 0.113 0.059
p 0.133 0.127 0.173 0.477
IL-27 rho 0.092 0.084 0.063 0.114
p 0.269 0.313 0.451 0.167
IL-35 rho 0.005 0.190 0.174 0.120
p 0.951 0.021 0.036 0.147
TGF-β1 rho −0.154 −0.116 −0.084 −0.141
p 0.064 0.163 0.313 0.088
sTNF-R1 rho 0.115 0.138 0.188 0.222 *
p 0.166 0.970 0.023 0.007 *
sTNF-R2 rho −0.099 −0.059 −0.025 −0.116
p 0.236 0.483 0.762 0.160

Breg: immunoregulatory B cells; Tr1: T regulatory type 1 cells; M2: alternatively activated macrophage. All cytokines are expressed as pg/mL. Correlation performed by Spearman’s correlation. * Significant at p-value < 0.01.