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. 2024 Aug 9;25(16):8710. doi: 10.3390/ijms25168710

Figure 7.

Figure 7

The presented data show the change in animal body weight measured on days 7, 14, 21, and 28 of the pivotal experiment. The experimental animals were divided as follows: HC—healthy control group; AA—group of untreated controls with adjuvant arthritis (AA); MTX—rats with AA treated with methotrexate (MTX) at a dose of 0.3 mg/kg twice weekly; ASTAP—group of rats with AA receiving astaxanthin of natural origin in the oral dose of 20 mg/kg daily, ASTAP + MTX—group of rats with AA receiving astaxanthin of natural origin in the oral dose of 20 mg/kg daily and in a combination with MTX at a dose of 0.3 mg/kg twice weekly; ASYN—group of rats with AA receiving synthetic astaxanthin in the oral dose of 20 mg/kg daily; ASYN + MTX—group of rats with AA receiving synthetic astaxanthin in the oral dose of 20 mg/kg daily and in combination with MTX at a dose of 0.3 mg/kg twice weekly; BEKA—group of rats with AA receiving β-carotene in the oral dose of 20 mg/kg daily; KXAN—group of rats with AA receiving β-cryptoxanthin in the oral dose of 10 μg/kg daily. Data are expressed as mean ± SEM. Statistical significance was evaluated using ANOVA for independent variables: *** p < 0.001 vs. HC group, ++ p < 0.01 vs. AA group.