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. 2024 Aug 22;25(16):9113. doi: 10.3390/ijms25169113
4E-BP1 eukaryotic translation initiation factor 4E-binding protein 1.
AGEs glycation end-products.
AMPK AMP-kinase.
AS160 (TBC1D4) Akt substrate of 160 kDa.
ASK1 apoptosis signal-regulating kinase 1.
ATF4 activating transcription factor 4.
ATF6 activating transcription factor-6.
ATF6f activating transcription factor-6 cytosolic fragment.
Bad BCL2-antagonist of cell death.
BiP immunoglobulin heavy-chain-binding protein.
BMI body mass index.
CCs and CXCs chemokines.
CHOP C/EBP homologous protein.
CREB cAMP-responsive element-binding protein.
CSFs colony-stimulating factors.
CVD cardiovascular disease.
DHA docosahexaenoic acid.
DPP-4 dipeptidyl-peptidase 4.
eIF2B eukaryotic initiation factor 2B.
eIF2α eukaryotic translation initiation factor 2α.
EPA eicosapentaenoic acid.
ER stress endoplasmic reticulum stress.
ERAD endoplasmic reticulum-associated degradation.
FFA fatty acid.
FOXOs forkhead transcription factors.
GADD153 growth-arrest and DNA-damage-inducible protein.
GAP GTPase-activating protein.
GCs glucocorticoids.
GEF guanine exchange factor.
GFs growth factors.
GH growth hormone.
GK glucokinase.
GLP glucagon-like peptide.
GLUT4 glucose transporter 4.
GRB2 growth factor receptor-bound protein 2.
GRP78 78 kDa glucose-regulated protein.
GS glycogen synthase.
GSK3 glycogen synthase kinase 3.
HDL-C high-density lipoprotein cholesterol.
HOMA-IR homeostasis model assessment of IR.
IFNs interferons.
IGF-1 insulin-like growth factor 1.
IGF-2 insulin-like growth factor 2.
IKKβ inhibitor of nuclear factor kappa-B kinase subunit beta.
IL-6 interleukin-6.
IR insulin resistance.
IRE1 inositol requiring enzyme 1.
IRS insulin receptor substrate.
JNK c-Jun N-terminal kinase.
LDL-C low-density lipoprotein cholesterol.
MAPK mitogen activated protein kinase.
MCP-1 monocyte chemoattractant protein-1.
MetS metabolic syndrome.
MIP-1 macrophage inflammatory protein 1.
MnSOD manganese superoxide dismutase
mTORC1 mammalian target of rapamycin complex 1.
MyD88 myeloid differentiation primary response gene 88.
NFκB nuclear factor κB.
NO nitrogen–monoxide.
OGTT oral glucose tolerance test.
PDK-1 phosphatidyl-inositol dependent kinase 1.
PEPCK phospho-enol-pyruvate carboxykinase
PERK PKR-like eukaryotic initiation factor 2α kinase
PGC-1α proliferator-activated receptor gamma coactivator 1α
PHLPPs PH domain and leucine rich repeat protein phosphatases
PI3K phosphatidylinositol-3-kinase
PIP2 phosphatidylinositol 4,5-bisphosphate
PIP3 phosphatidylinositol 3,4,5-trisphosphate
PKB protein kinase B.
PKC protein kinase C.
PKCλ and PKCζ PKC isomers.
PP2A protein phosphatase 2A
PP2B protein phosphatase 2B
PPARα and γ peroxisome proliferator-activated receptor α and γ.
PTEN phosphatase and tensin homolog deleted on chromosome ten
PTP1B protein tyrosine phosphatase 1B
PUFA polyunsaturated fatty acids
RAC1 Ras-related C3 botulinum toxin substrate 1.
ROS reactive oxygen species
S1P/S2P site-1 protease/ site-2 protease
S6K1 S6 kinase.
SCA sterol cleavage protein
SELENOP/SELENOS selenoprotein P/selenoprotein S.
Ser/Thr serine/threonine
SGLT2 sodium–glucose co-transporter-2
SHIP1/SHIP2 SH2 domain containing inositol 5’phosphatase 1 and 2.
SIRT1 sirtuin 1
SNP single nucleotide polymorphism
SOCS1/3 suppressor of cytokine signaling 1/3
SOS son of sevenless
SRE sterol regulatory element
SREBP sterol regulatory binding proteins
T1DM Type 1 Diabetes Mellitus
T2DM Type 2 Diabetes Mellitus
TBC1D1 AS160 paralog.
TGs triglycerides
TSC1/TSC2 tuberous sclerosis complex 1 and 2
UPR unfolded protein response
VLDL very-low-density lipoprotein
XBP1 X-box binding protein-1
Y tyrosine