| AAV | adeno-associated virus |
| ADCs | antibody-Drug Conjugates |
| ADME | absorption, distribution, metabolism, and excretion |
| AOCs | antibody-oligonucleotide conjugates |
| ASGPR | sialoglycoprotein receptor |
| ASO | antisense oligonucleotide |
| BCR | B-cell receptor |
| CAR | chimeric antigen receptors |
| ChAd68 | chimpanzee adenovirus |
| CLAN | cationic lipid-assisted nanoparticles |
| ctDNA | circulating tumor DNA |
| CTL | cytotoxic T lymphocytes |
| DBCO | dibenzoazacyclooctyne |
| DC | dendritic cell |
| EMA | European Medicines Agency |
| FDA | Food and Drug Administration |
| GalNAc | N-acetylgalactosamine |
| hATTR | hereditary transthyretin amyloidosis |
| HCC | hepatocellular carcinoma |
| HIV | human immunodeficiency virus |
| HO1 | heme oxygenase-1 |
| ICD | immunogenic cell death |
| ICIs | immune checkpoint inhibitors |
| IL-12 | interleukin-12 |
| LNPs | Lipid Nanoparticles |
| L-PPSN | polyethylenimine-modified porous silica nanoparticle |
| MARV | Marburg virus |
| MDSCs | Myeloid-derived suppressor cells |
| mRNA | messenger RNA |
| MSNs/MSNPs | mesoporous silica nanoparticles |
| MSS-CRC | microsatellite-stable colorectal cancer |
| PCL | poly(ε-caprolactone) |
| PD-L1 | programmed cell death protein 1 |
| PEG | polyethylene glycol |
| PEI | polyethyleneimine |
| PGs | poly(glycerols) |
| PHEMA | poly(2-hydroxyethyl methacrylate) |
| PHPMA | poly(hydroxypropyl methacrylate) |
| PLGA | poly(lactic-co-glycolic acid) |
| PMDA | Pharmaceuticals and Medical Devices Agency |
| PMO | morpholine oligonucleotide |
| POX | poly(oxazolines) |
| samRNA | self-amplifying RNA |
| siRNA | small interference RNA |
| SIV | simian immunodeficiency virus |
| SSNs | spiked silica nanoparticle |
| TAMs | tumor-associated macrophages |
| TCRs | T cell receptors |
| TDLN | tumor draining lymph node |
| TfR1 | transferrin receptor 1 |
| TLR | Toll-like receptors |
| TME | tumor microenvironment |
| TTR | transthyretin |
| VLP | virus-like particle |