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. 2024 Aug 15;25(16):8888. doi: 10.3390/ijms25168888
AAV adeno-associated virus
ADCs antibody-Drug Conjugates
ADME absorption, distribution, metabolism, and excretion
AOCs antibody-oligonucleotide conjugates
ASGPR sialoglycoprotein receptor
ASO antisense oligonucleotide
BCR B-cell receptor
CAR chimeric antigen receptors
ChAd68 chimpanzee adenovirus
CLAN cationic lipid-assisted nanoparticles
ctDNA circulating tumor DNA
CTL cytotoxic T lymphocytes
DBCO dibenzoazacyclooctyne
DC dendritic cell
EMA European Medicines Agency
FDA Food and Drug Administration
GalNAc N-acetylgalactosamine
hATTR hereditary transthyretin amyloidosis
HCC hepatocellular carcinoma
HIV human immunodeficiency virus
HO1 heme oxygenase-1
ICD immunogenic cell death
ICIs immune checkpoint inhibitors
IL-12 interleukin-12
LNPs Lipid Nanoparticles
L-PPSN polyethylenimine-modified porous silica nanoparticle
MARV Marburg virus
MDSCs Myeloid-derived suppressor cells
mRNA messenger RNA
MSNs/MSNPs mesoporous silica nanoparticles
MSS-CRC microsatellite-stable colorectal cancer
PCL poly(ε-caprolactone)
PD-L1 programmed cell death protein 1
PEG polyethylene glycol
PEI polyethyleneimine
PGs poly(glycerols)
PHEMA poly(2-hydroxyethyl methacrylate)
PHPMA poly(hydroxypropyl methacrylate)
PLGA poly(lactic-co-glycolic acid)
PMDA Pharmaceuticals and Medical Devices Agency
PMO morpholine oligonucleotide
POX poly(oxazolines)
samRNA self-amplifying RNA
siRNA small interference RNA
SIV simian immunodeficiency virus
SSNs spiked silica nanoparticle
TAMs tumor-associated macrophages
TCRs T cell receptors
TDLN tumor draining lymph node
TfR1 transferrin receptor 1
TLR Toll-like receptors
TME tumor microenvironment
TTR transthyretin
VLP virus-like particle