Table 3.
Clinical Endpoint Reached (n = 80) |
Clinical Endpoint Missed (n = 21) |
p-Value | |
---|---|---|---|
Age, years | 81.6 [76.7–84.6] (80/80) |
84.5 [77.9–88.9] (21/21) |
0.067 |
Height, cm | 165.3 ± 9.3 (80/80) |
168.1 ± 8.2 (21/21) |
0.216 |
Weight, kg | 74.5 [65.0–88.0] (80/80) |
67 [61.5–80.5] (21/21) |
0.194 |
BMI, kg/m2 | 27.3 [24.2–31.1] (80/80) |
24.5 [21.9–29.1] (21/21) |
0.036 |
Male | 31 (38.8%) (80/80) |
14 (66.7%) (21/21) |
0.022 |
Known coronary artery disease |
29 (36.3%) (80/80) |
15 (71.4%) (21/21) |
0.004 |
Prior PCI | 17 (21.3%) (80/80) |
12 (57.1%) (21/21) |
0.001 |
Arterial hypertension | 69 (86.3%) (80/80) |
18 (85.7%) (21/21) |
0.950 |
Diabetes | 23 (28.7%) (80/80) |
5 (23.8%) (21/21) |
0.653 |
Hyperlipidemia | 49 (61.3%) (80/80) |
12 (57.1%) (21/21) |
0.732 |
ICD or pacemaker | 3 (3.8%) (80/80) |
1 (4.8%) (21/21) |
0.832 |
COPD | 5 (6.3%) (80/80) |
1 (4.8%) (21/21) |
0.797 |
Dialysis | 0 (80/80) |
1 (4.8%) (21/21) |
0.050 |
eGFR, mL/min | 60 ± 20 (80/80) |
54 ± 20 (21/21) |
0.250 |
CKD stage
|
4 (5.0%) 34 (42.5%) 38 (47.5%) 4 (5.0%) 0 (80/80) |
1 (4.8%) 7 (33.3%) 11 (52.4%) 1 (4.8%) 1 (4.8%) (21/21) |
0.375 |
Troponin T, ng/L | 22 [15–73] (80/80) |
29 [16–45] (21/21) |
0.364 |
NT-pro BNP pg/L | 1328 [536–4734] (77/80) |
1587 [459–7993] (21/21) |
0.396 |
LVEF
|
53 (66.3%) 6 (7.5%) 7 (8.8%) 14 (17.5%) (80/80) |
12 (57.1%) 4 (19.0%) 1 (4.8%) 4 (19.0%) (21/21) |
0.422 |
Atrial fibrillation or flutter | 36 (45.0%) (80/80) |
13 (61.9%) (21/21) |
0.168 |
Coronary CT-Angiography | |||
Heart rate during acquisition, bpm | 74 ± 12 (75/80) |
73 ± 13 (19/21) |
0.764 |
mAS | 7932 [5968–9373] (80/80) |
7593 [5360–9009] (21/21) |
0.547 |
DLP, mGycm | 640 [414–811] (80/80) |
521 [299–677] (21/21) |
0.098 |
Contrast, mL | 76 [71–86] (80/80) |
71 [71–76] (21/21) |
0.007 |
Cardiac mass, g | 195 [167–246] (80/80) |
173 [137–215] (21/21) |
0.098 |
Invasive Coronary Angiography | |||
Coronary artery disease none 1-vessel 2-vessel 3-vessel |
45 (56.3%) 10 (12.5%) 7 (8.8%) 18 (22.5%) (80/80) |
3 (14.3%) 6 (28.6%) 5 (23.8%) 7 (33.3%) (21/21) |
0.005 |
BMI = body mass index, bpm = beats per minute, cCTA = computed coronary tomography angiography, COPD = chronic obstructive pulmonary disease, CKD = chronic kidney disease, DLP = dose length product, eGFR = estimated glomerular filtration rate, ICA = invasive coronary angiography, ICD = implantable cardioverter defibrillator, LVEF = left ventricular ejection fraction, mAs = milliampere-seconds, PCI = percutaneous coronary intervention, TAVI = transcatheter aortic valve implantation. p-values < 0.05 are presented bold. Data availability is displayed in brackets below for each variable.