Table 1.
Comparative studies currently available on the management of CD-associated strictures.
| Study Design | Strictures Location | Treatment and No of Pts |
Technical Success Rate | Long-Term Outcomes (Years fu) |
Adverse Events, % | |
|---|---|---|---|---|---|---|
| [17] 2017 | Retrospective | Ileocolic anastomosis | 176 EBD 131 surgery |
- | average time to surgery/re-surgery delayed by 6.45 years in EBD group | 1.1 (perforation) 8.8 (~infection) |
| [18] 2024 | Retrospective | Duodenal | 30 EBD 18 surgery |
- | 2.96 years recurrence-free 6.31 years recurrence-free, p = 0.01 |
0.74 16.67 |
| [19] 2018 | Retrospective | Anastomosis (85.7% ileocolic) | 21 ES 164 EBD |
100% 89.5% |
9.5% surgery (0.8) 33.5% re-surgery (4) |
8.8 (bleeding) 1.1 (perforation) |
| [20] 2019 | Retrospective | Ileocolic anastomosis | 35 ES 147 ICR |
- | 11.3% surgery (0.8) 10.2% re-surgery (2.2), p = 0.83 |
10.2 (~bleeding) 31.9 (~ileus) |
| [21] 2020 | Retrospective | Distal ileum, ileocecal valve | 13 ES 32 ICR |
100% 100% |
15.4% surgery (1.8) 18.8% re-surgery (1.5), p = 0.79 |
6,9 (perforation) 25 (~infection) |
| [22] 2022 | Randomized trial | - | 41 EBD 39 FCSEMS |
- | 80% no re-intervention (1) 51% no re-intervention (1), p = 0.0061 |
2 (perforation) 3 (perforation) |
ES, endoscopic electroincision; EBD, endoscopic balloon dilation; FCSEMS, fully-covered self-expandable metallic stents; fu, follow-up ICR, ileocolic resection; p, p-value; pts, patients; ~, most frequent.