Table 1.

Statistically significant (padj < 0.05) species in the three comparisons: OC vs. PAI-3, OC vs. PAI-1 and PAI-1 vs. PAI-3.

Species	OC vs. PAI-3	OC vs. PAI-1	PAI-1 vs. PAI-3
Fusobacterium periodonticum	↓ 1	↓	-
Prevotella melaninogenica	↓	↓	-
Haemophilus parainfluenzae	↓	↓	-
Granulicatella adiacens	↓	↓	-
Porphyromonas pasteri	↓	↓	-
Leptotrichia sp. HMT_215	↓	↓	-
Rothia mucilaginosa	↓	↓	-
Prevotella nanceiensis	↓	↓	-
Campylobacter concisus	↓	↓	-
Gemella sanguinis	↓	↓	-
Streptococcus parasanguinis_clade_411	↓	↓	-
Bergeyella sp._HMT_322	↓	↓	-
Leptotrichia hongkongensis	↓	↓	-
Saccharibacteria_(TM7)_[G-1] bacterium_HMT_352	↓	-	-
Rothia dentocariosa	↓	↓	-
Lachnoanaerobaculum umeaense	↓	↓	-
Fusobacterium nucleatum_subsp. vincentii	↓	↓	-
Corynebacterium matruchotii	↓	↓	-
Capnocytophaga gingivalis	↓	↓	-
Capnocytophaga leadbetteri	↓	↓	-
Veillonella atypica	↓	↓	-
Lautropia mirabilis	↓	↓	-
Prevotella intermedia	↓	↓	-
Streptococcus salivarius	↓	↓	-
Dialister invisus	↑	↑	-
Veillonella dispar	↓	↓	-
Slackia exigua	↑	-	-
Prevotella salivae	↓	↓	-
Atopobium parvulum	↓	-	-
Pseudoramibacter alactolyticus	↑	-	↑
Prevotella nigrescens	↓	↓	-
Prevotella pallens	↓	↓	-
Saccharibacteria_(TM7)_[G-3] bacterium_HMT_351	↓	-	-
Veillonella rogosae	↓	-	-
Ruminococcaceae_[G-2] bacterium_HMT_085	↓	-	-
Olsenella uli	↑	-	-
Gemella morbillorum	↓	-	-
Capnocytophaga sp. HMT_326	↓	-	-
Alloprevotella sp. HMT_308	↓	-	-
Bacteroidales_[G-2] bacterium_HMT_274	↓	-	-
Bacteroidaceae_[G-1] bacterium_HMT_272	↑	-	-
Veillonella parvula	↓	↓	-
Stomatobaculum sp. HMT_097	↓	-	-
Ruminococcaceae_[G-1] bacterium_HMT_075	↓	↓	-
Megasphaera micronuciformis	↓	-	-
Prevotella sp. HMT_317	↓	↓	-
Schaalia sp. HMT_180	↓	↓	-
Saccharibacteria_(TM7)_[G-5] bacterium_HMT_356	↓	-	-
Capnocytophaga sputigena	↓	↓	↓
Catonella morbi	↓	-	-
Fretibacterium fastidiosum	↑	-	-
Rothia aeria	↓	-	-
Cardiobacterium hominis	↓	↓	-
Oribacterium sp. HMT_102	↑	-	-
Capnocytophaga granulosa	↓	↓	-
Granulicatella elegans	↓	-	-
Kingella oralis	↓	↓	-
Selenomonas sputigena	↓	-	-
Haemophilus sputorum	↓	-	-
Prevotella sp. HMT_396	↓	-	-
Campylobacter gracilis	↓	↓	-
Tannerella forsythia	↓	↓	-
Leptotrichia sp._HMT_417	↓	-	-
Corynebacterium durum	↓	-	-
Prevotella denticola	↓	-	-
Porphyromonas endodontalis	↓	-	-
Peptostreptococcaceae_[XI][G-1] [Eubacterium]_infirmum	↑	-	-
Abiotrophia defectiva	↓	-	-
Alloprevotella sp._HMT_914	↓	-	-
Treponema denticola	↓	-	-
Haemophilus sp._HMT_036	↓	↓	-
Lachnospiraceae_[G-3] bacterium_HMT_100	↓	-	-
Alloprevotella sp._HMT_473	↓	-	-
Tannerella sp._HMT_286	↓	↓	-
Actinomyces graevenitzii	↓	-	-
Dialister pneumosintes	↑	-	-
Prevotella baroniae	↑	-	-
Paracoccus yeei	↑	↑	-
Neisseria elongata	↓	-	-
Filifactor alocis	↓	-	-
Prevotella sp._HMT_300	↓	-	-
Prevotella oulorum	↓	↓	-
Bacteroidetes_[G-5] bacterium_HMT_511	↓	-	-
Anaeroglobus geminatus	↑	-	-
Mycoplasma faucium	↓	-	-
Selenomonas noxia	-	↓	-
Enterococcus casseliflavus	-	↑	-

¹ The ↓ indicates a significant decreased abundance, while ↑ indicates a significant increased abundance in the second group in comparison with the first one.