Table 6.
Moderated mediation model of household enteric pathogen transmission pathways and HAZ at 60-day follow-up among 706 children 24–59 months of age in the control cohort in Kolkata, India.
| Dependent Variable | Independent Variable | Path Coefficient | 95% CI 1 | One Tailed p-Value |
|---|---|---|---|---|
| HAZ (60 days) 2 | Norovirus GII | −0.04 | (−0.07, −0.01) | <0.01 |
| Hands washed before nursing | 0.08 | (0.02, 0.14) | <0.01 | |
| Water stored | 0.23 | (0.10, 0.36) | <0.00 | |
| Child feces disposed | 0.03 | (−0.08, 0.08) | 0.06 | |
| Water source in house | −0.08 | (−0.21, 0.05) | 0.11 | |
| Hands washed before cooking | −0.02 | (−0.07, 0.03) | 0.18 | |
| Caretaker received formal education | 0.05 | (0.01, 0.10) | 0.01 | |
| Norovirus GII | Handwashing after child defecation | −0.46 | (−0.93, −0.07) | <0.00 |
| Handwashing before nursing | 0.60 | (0.04, 1.16) | 0.01 | |
| Use of soap | 0.90 | (−0.22, 0.56) | 0.17 | |
| Water stored | −0.34 | (−0.21, 0.70) | 0.23 | |
| Water stored | Child feces disposed | 0.03 | (0.01, 0.06) | 0.01 |
| Water treated | 0.09 | (0.0, −0.17) | 0.00 | |
| Indirect effects of household reservoirs and hygiene behaviors 3 | ||||
| Child feces disposal mediated by stored water | 0.01 | (0.01, 0.02) | 0.02 | |
| Water treatment mediated by stored water | 0.02 | (0.01, 0.04) | 0.01 | |
| Handwashing after child defecation mediated by Norovirus GII |
0.02 | (0.01, 0.04) | 0.02 | |
| Handwashing before nursing mediated by Norovirus GII |
−0.02 | (−0.07, −0.01) | <0.00 | |
1 Bayesian credibility interval. 2 Child’s age, sex, breastfeeding status at baseline, baseline HAZ, and length of follow-up. included in pathway. 3 Indirect effects represent pathogen-specific transmission pathways leading to children’s exposure to enteric infections and growth impairment. Indirect effects calculated by multiplying coefficients for respective paths a × b in Figure 3B.