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. 2024 Aug 10;17(8):1056. doi: 10.3390/ph17081056

Table 3.

Crude and adjusted odds ratios (95% confidence interval) of lipophilic statin prescription (per 1 year) for overall migraines, migraines with aura, and migraines without aura.

Characteristics OR (95% CI)
Crude † p Model 1 †‡ p Model 2 †§ p
OR of lipophilic statins for overall migraines 1.04 (1.02–1.07) <0.001 * 0.94 (0.92–0.96) <0.001 * 0.94 (0.92–0.97) <0.001 *
OR of lipophilic statins for migraines with aura 0.86 (0.74–1.00) 0.046 * 0.76 (0.65–0.88) <0.001 * 0.75 (0.64–0.88) <0.001 *
OR of lipophilic statins for migraines without aura 1.05 (1.03–1.07) <0.001 * 0.95 (0.92–0.97) <0.001 * 0.95 (0.93–0.97) <0.001 *

Abbreviations: OR, odds ratio; 95% CI, 95% confidence interval. * Conditional logistic regression model, significant at p < 0.05. † Models were stratified by age, sex, income, and region of residence. ‡ Model 1 was adjusted for systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, and hemoglobin level. § Model 2 was adjusted for Model 1 plus obesity, smoking, alcohol consumption, and Charlson Comorbidity Index (CCI) score.