Table 3.
Crude and adjusted odds ratios (95% confidence interval) of lipophilic statin prescription (per 1 year) for overall migraines, migraines with aura, and migraines without aura.
Characteristics | OR (95% CI) | |||||
---|---|---|---|---|---|---|
Crude † | p | Model 1 †‡ | p | Model 2 †§ | p | |
OR of lipophilic statins for overall migraines | 1.04 (1.02–1.07) | <0.001 * | 0.94 (0.92–0.96) | <0.001 * | 0.94 (0.92–0.97) | <0.001 * |
OR of lipophilic statins for migraines with aura | 0.86 (0.74–1.00) | 0.046 * | 0.76 (0.65–0.88) | <0.001 * | 0.75 (0.64–0.88) | <0.001 * |
OR of lipophilic statins for migraines without aura | 1.05 (1.03–1.07) | <0.001 * | 0.95 (0.92–0.97) | <0.001 * | 0.95 (0.93–0.97) | <0.001 * |
Abbreviations: OR, odds ratio; 95% CI, 95% confidence interval. * Conditional logistic regression model, significant at p < 0.05. † Models were stratified by age, sex, income, and region of residence. ‡ Model 1 was adjusted for systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, and hemoglobin level. § Model 2 was adjusted for Model 1 plus obesity, smoking, alcohol consumption, and Charlson Comorbidity Index (CCI) score.