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. 2024 Aug 10;17(8):1056. doi: 10.3390/ph17081056

Table 4.

Crude and adjusted odds ratios (95% confidence interval) of hydrophilic statin prescription (per 1 year) for overall migraines, migraines with aura, and migraines without aura.

Characteristics OR (95% CI)
Crude † p Model 1 †‡ p Model 2 †§ p
OR of hydrophilic statins for overall migraines 1.01 (0.97–1.05) 0.579 0.92 (0.88–0.96) <0.001 * 0.92 (0.88–0.96) <0.001 *
OR of hydrophilic statins for migraines with aura 0.80 (0.55–1.17) 0.254 0.71 (0.49–1.04) 0.077 0.71 (0.49–1.04) 0.080
OR of hydrophilic statins for migraines without aura 1.01 (0.97–1.06) 0.485 0.92 (0.88–0.96) <0.001 * 0.93 (0.89–0.96) <0.001 *

Abbreviations: OR, odds ratio; 95% CI, 95% confidence interval. * Conditional logistic regression model, significant at p < 0.05. † Models were stratified by age, sex, income, and region of residence. ‡ Model 1 was adjusted for systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, and hemoglobin level. § Model 2 was adjusted for Model 1 plus obesity, smoking, alcohol consumption, and Charlson Comorbidity Index (CCI) score.