Table 2.

Antibiofilm activities of dispersin B against bacteria in vitro.

Species	Antibiofilm Activity	References
Achromobacter xylosoxidans	Inhibits biofilm formation; detaches preformed biofilms.	[82]
Acinetobacter baumannii	Inhibits “pellicle” formation at the air–liquid interface; inhibits biofilm formation; detaches preformed biofilms; sensitizes preformed biofilms to killing by antimicrobial peptide KSL-W.	[83,84]
Actinobacillus pleuropneumoniae	Inhibits biofilm formation; detaches preformed biofilms; sensitizes preformed biofilms to killing by ampicillin.	[14,15,50,85,86,87,88,89,90]
Aggregatibacter actinomycetemcomitans	Sensitizes planktonic cells to killing by human macrophages; sensitizes preformed biofilms to detachment by EDTA, SDS, proteinase K, and DNase; sensitizes preformed biofilms to killing by cetylpyridinium chloride and SDS; sensitizes preformed biofilms to killing by predatory Bdellovibrio bacteriovorus bacteria.	[91,92,93,94]
Bordetella pertussis, B. parapertussis	Inhibits biofilm formation; detaches preformed biofilms; sensitizes preformed biofilms to killing by antimicrobial peptides polymyxin B and LL-37.	[82,95,96,97]
Burkholderia cepacia complex	Inhibits biofilm formation; detaches preformed biofilms; sensitizes biofilms to killing by tobramycin.	[43,98]
Corynebacterium striatum	Detaches preformed biofilms.	[77]
Cutibacterium acnes	Inhibits surface attachment and biofilm formation; sensitizes biofilms to killing by benzoyl peroxide and tetracycline.	[99]
Escherichia coli	Inhibits biofilm formation; detaches preformed biofilms; sensitizes biofilms to killing by triclosan and bacteriophages.	[61,73,75,78,100,101]
Francisella novicida, F. philomiragia	Detaches preformed biofilms.	[102]
Klebsiella pneumoniae	Inhibits biofilm formation; sensitizes preformed biofilms to killing by antimicrobial peptide KSL-W.	[83,103]
Pectobacterium atrosepticum, P. carotovorum	Inhibits biofilm formation; detaches preformed biofilms.	[104,105]
Pseudomonas fluorescens	Inhibits biofilm formation; detaches preformed biofilms; inhibits attachment of planktonic cells to tomato roots.	[101]; J. B. Kaplan, unpublished data
Ralstonia solanacearum	Inhibits biofilm formation.	J. B. Kaplan, unpublished data
Solobacterium moorei	Inhibits biofilm formation.	[106]
Staphylococcus aureus	Inhibits biofilm formation; detaches preformed biofilms; sensitizes preformed biofilms to killing by triclosan, tobramycin, vancomycin, rifampicin, clindamycin, cefamandole nafate, and antimicrobial peptide KSL-W.	[60,61,83,103,107,108,109,110,111]
Staphylococcus capitis	Detaches preformed biofilms.	[112]
Staphylococcus epidermidis	Inhibits biofilm formation; detaches preformed biofilms; sensitizes preformed biofilms to killing by triclosan, cetylpyridinium chloride, ciprofloxacin, rifampicin, and antimicrobial peptide KSL-W.	[50,55,59,61,82,83,100,103,108,109,112,113,114,115,116,117,118]
Staphylococcus pseudintermedius	Inhibits biofilm formation; detaches preformed biofilms.	[119]
Streptococcus mutans	Detaches preformed biofilms; sensitizes preformed biofilms to detachment by oral irrigation.	[120]
Streptomyces coelicolor, S. lividans	Inhibits surface attachment and hyphal aggregation.	[121]
Xanthomonas citri	Disaggregates bacterial flocs (floating or suspended biofilms).	J. B. Kaplan, unpublished data
Yersinia pestis	Inhibits biofilm formation.	[101]