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. 2024 Jul 27;17(8):993. doi: 10.3390/ph17080993

Table 7.

The antidiabetic effects of Halodule uninervis.

Extract Dose Experimental Model Observations References
Ethanolic extract 125, 250, 500, 1000, and 2000 ppm In vitro inhibition of α-glucosidase enzyme assay
  • -

    IC50 is 74.99 ppm

 [69]
Ethyl acetate extract 125, 250, 500, 1000, and 2000 ppm In vitro inhibition of α-glucosidase enzyme assay
  • -

    IC50 is 1517.05 ppm

 [69]
Methanolic extract 150 and 250 mg/kg Streptozotocin-induced diabetic mouse model
  • -

    Dose-dependent decrease in serum glucose levels.

  • -

    Recovered weight loss and low white blood cell count.

  • -

    Enhanced liver and kidney functions.

 [70]