Table 1.
Descriptive statistics of the anthropometric before (pre) and after (post) 12 weeks of LFD in the whole group and subgroups of IBS-D patients according to their normal (N-FZ) or high (H-FZ) fecal zonulin levels at baseline.
| Total Pre (n = 38) |
Total Post (n = 38) |
p | N-FZ Pre (n = 20) |
N-FZ Post (n = 20) |
p | H-FZ Pre (n = 18) |
H-FZ Post (n = 18) |
p | |
|---|---|---|---|---|---|---|---|---|---|
| Weight (kg) | 65.4 ± 1.9 | 62.0 ± 1.8 | <0.0001 | 64.0 ± 2.4 | 61.1 ± 2.3 | <0.0001 | 67 ± 3.0 | 62.9 ± 2.8 | <0.0001 |
| Height (m) | 1.61 ± 0.01 | 1.61 ± 0.01 | 1.59 ± 0.01 | 1.59 ± 0.01 | 1.63 ± 0.02 | 1.63 ± 0.02 | |||
| BMI (kg/m2) | 25.1 ± 0.7 | 23.8 ± 0.7 | <0.0001 | 25.2 ± 0.9 | 24.1 ± 0.8 | <0.0001 | 25.0 ± 1.1 | 23.5 ± 1.2 | <0.0001 |
| Waist circumference (cm) | 79.3 ± 1.3 | 76.3 ± 1.7 | <0.0001 | 79.4 ± 2.5 | 76.9 ± 2.1 | 0.0027 | 79.1 ± 3.1 | 75.6 ± 2.9 | 0.0001 |
LFD = low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet. BMI = body mass index. Data presented as the means ± SEM. Data from before and after treatment were compared using the Wilcoxon signed-rank test. The two subgroups were compared both before and after the diet using the Mann–Whitney test. Differences considered significant at p < 0.05.