Table 3.
Variable | Univariate Regression Analysis Coefficient (95% CI) | p-Value * | Multivariate Analysis Coefficient (95%CI) ** | p-Value * |
---|---|---|---|---|
Gender | 0.02 | 0.59 | ||
Male | 0 (reference) | 0 (reference) | ||
Female | −4.26 (−7.80, −0.73) | −0.75 (−3.47, 1.98) | ||
Age at enrolment (years) | 0.13 (0.03–0.23) | 0.01 | 0.01 (−0.07, 0.09) | 0.79 |
Clinical pattern at diagnosis | ||||
Classical | 0 (reference) | - | ||
Non-classical | −0.32 (−4.78–4.14) | 0.89 | ||
Silent | −3.66 (−12.31–4.99) | 0.41 | ||
Disease duration (years) | 0.11 (−0.04–0.27) | 0.15 | ||
Educational level | 1.00 | |||
No academic degree | 0 (reference) | |||
Academic degree | 0.00 (−3.19–3.19) | |||
Marital status | 0.02 | 0.34 | ||
Stable relationship | 0 (reference) | 0 (reference) | ||
No stable relationship | −4.06 (−7.35, −0.76) | −1.31 (−4.05, 1.41) | ||
Persistent symptoms despite a GFD | −2.46 (−6.02–1.11) | 0.18 | ||
Membership of the Italian Coeliac Association | −1.38 (−4,73–1.97) | 0.42 | ||
Good GFD adherence | 4.09 (−2.69–10.88) | 0.24 | ||
CD-QOL | 0.35 (0.23–0.46) | <0.001 | 0.04 (−0.06, 0.15) | 0.40 |
STAI-Y1 | −0.62 (−073,−0.51) | <0.001 | −0.88 (−0.25, 0.08) | 0.31 |
STAI-Y2 | −0.83 (−0.93, −0.72) | <0.001 | −0.98 (−1.14, −0.81) | <0.001 |
BDI | −0.69 (−0.85, −0.54) | <0.001 | 0.23 (0.03–0.44) | 0.02 |
GFD: gluten-free diet adherence. * p-value <0.05 for significance. ** Backward elimination multivariate regression analysis.