CENTRAL	PubMed	EMBASE (Ovid)	CINAHL (EBSCO)
1. OTITIS‐MEDIA (MeSH, explode all trees) 2. (otitis NEXT media) OR (glue NEXT ear) 3. (serous NEAR otitis) OR (secretory NEAR otitis) 4. SOM OR OME 5. 1 OR 2 OR 3 OR 4 6. EAR‐DISEASES (MeSH, explode all trees) 7. otitis OR inflam* OR effusion* OR infect* OR suppurat* OR secret* OR pressure 8. 6 OR 7 9. EAR‐MIDDLE (MeSH, explode all trees) 10. (middle NEAR ear*) OR (eustachian NEXT tube*) 11. 9 OR 10 12. 8 AND 11 13. 5 OR 12 14. MIDDLE‐EAR‐VENTILATION (MeSH, explode all trees) 15. INSUFFLATION (MeSH) 16. VALSALVA‐MANEUVER (MeSH) 17. autoinflat* OR (auto NEXT inflat*) OR (ear* NEAR inflat*) OR (ear* NEAR aerat*) OR (ME NEXT inflat*) OR (air NEXT inflat*) 18. (nose OR nasal) AND balloon 19. valsalva OR politzer OR popper 20. open* NEAR eustachian 21. insufflat* 22. 14 OR 15 OR 16 OR 17 OR 18 OR 19 OR 20 OR 21 23. 13 AND 22	#1 "Otitis Media"[Mesh] #2 "otitis media" [tiab] OR "glue ear" [tiab] #3 (serous [tiab] OR secretory [tiab]) AND otitis [tiab] #4 SOM [tiab] OR OME [tiab] #5 #1 OR #2 OR #3 OR #4 #6 "Ear Diseases"[Mesh] #7 otitis [tiab] OR inflam* [tiab] OR effusion* [tiab] OR infect* [tiab] OR suppurat* [tiab] OR secret* [tiab] or pressure [tiab] #8 #6 OR #7 #9 "Ear, Middle"[Mesh] #10 (middle [tiab] AND ear* [tiab]) OR (eustachian [tiab] AND tube* [tiab]) #11 #9 OR #10 #12 #8 AND #11 #13 #5 OR #12 #14 "Middle Ear Ventilation"[Mesh] #15 "Insufflation"[Mesh] #16 "VALSALVA MANEUVER"[Mesh] #17 autoinflat* [tiab] OR ((auto [tiab] OR ear* [tiab] OR ME [tiab] OR air [tiab]) AND (inflat* [tiab] OR aerat* [tiab])) #18 (nose [tiab] OR nasal [tiab]) AND balloon [tiab] #19 valsalva [tiab] OR politzer [tiab] #20 open* [tiab] AND eustachian* [tiab] #21 insufflat* [tiab] OR popper [tiab] #22 #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 #23 #13 AND #22	1 exp *Otitis Media/ 2 ((otitis adj media) or (glue adj ear)).tw. 3 ((secretory or serous) adj otitis).tw. 4 (SOM or OME).tw. 5 exp Ear Disease/ 6 (otitis or inflam* or effusion* or infect* or suppurat* or secret* or pressure).tw. 7 6 or 5 8 exp Middle Ear/ 9 ((middle and ear*) or (eustachian and tube*)).tw. 10 8 or 9 11 7 and 10 12 11 or 4 or 1 or 3 or 2 13 middle ear ventilation/ 14 aeration/ 15 valsalva maneuver/ 16 (autoinflat* or ((auto or ear* or ME or air) and (inflat* or aerat*))).tw. 17 ((nose or nasal) and balloon).tw. 18 (valsalva or politzer).tw. 19 (open* and eustachian*).tw. 20 (insufflat* OR popper).tw. 21 17 or 20 or 15 or 14 or 18 or 13 or 16 or 19 22 21 and 12	S1 (MH "Otitis Media+") S2 TX otitis AND media S3 TX glue AND ear S4 TX SOM OR OME S5 TX "secretory otitis" OR "serous otitis" S6 otitis OR inflam* OR effusion* OR infect* OR suppurat* OR secret* or pressure S7 (MH "Ear Diseases+") S8 s6 OR s7 S9 (MH "Ear, Middle+") S10 TX "middle ear" OR "eustachian tube" S11 S9 OR s10 S12 s8 and s11 S13 S1 OR s2 OR s3 OR s4 OR s5 OR s12 S14 (MH "Middle Ear Ventilation") S15 (MH "Insufflation") S16 (MH "Valsalva's Maneuver") S17 TX autoinflat* S18 TX auto OR ear OR ME OR air S19 TX inflat* OR aerat* S20 TX insufflat* S21 TX "nose balloon" OR "nasal balloon" S22 TX valsalva OR politzer OR popper S23 TX open AND eustachian s24 s14 OR s15 OR s16 OR s17 OR s18 OR s19 OR s20 OR s21 OR s22 OR s23 s25 s13 AND s24
Cochrane Ear, Nose and Throat Disorders Group Trials Register	Web of Science/BIOSIS Previews (Web of Knowledge)	CAB Abstracts (Ovid)	ICTRP
((otitis OR ear*) AND (autoinflat* OR insufflat* OR aeration OR valsalva OR inflat* OR popper OR politzer* OR balloon))	TI=((otitis OR ear*) AND (autoinflat* OR insufflat* OR aeration OR valsalva OR inflat* OR popper OR politzer*)) NB the last search on BIOSIS Previews was conducted in June 2012.	1 exp *Otitis Media/ 2 ((otitis adj media) or (glue adj ear)).tw. 3 ((secretory or serous) adj otitis).tw. 4 (SOM or OME).tw. 5 exp Ear Disease/ 6 (otitis or inflam* or effusion* or infect* or suppurat* or secret* or pressure).tw. 7 6 or 5 8 exp Middle Ear/ 9 ((middle and ear*) or (eustachian and tube*)).tw. 10 8 or 9 11 7 and 10 12 11 or 4 or 1 or 3 or 2 13 middle ear ventilation/ 14 aeration/ 15 valsalva maneuver/ 16 (autoinflat* or ((auto or ear* or ME or air) and (inflat* or aerat*))).tw. 17 ((nose or nasal) and balloon).tw. 18 (valsalva or politzer).tw. 19 (open* and eustachian*).tw. 20 (insufflat* OR popper).tw. 21 17 or 20 or 15 or 14 or 18 or 13 or 16 or 19 22 21 and 12	ear AND inflation OR ear AND autoinflation OR ear AND insufflation OR ear AND popper OR ear AND politzer OR ear AND balloon OR ear AND valsalva otitis AND inflation OR otitis AND autoinflation OR otitis AND insufflation OR otitis AND popper OR otitis AND politzer OR otitis AND balloon OR otitis AND valsalva