Table 2. Causes of pediatric carpal tunnel syndrome.

* Most cases are attributed to genetic conditions

** Lysosomal storage diseases

HNPP, hereditary neuropathy with liability to pressure palsies; ML, mucolipidosis; MPS, mucopolysaccharidosis

Sources: Costales et al. (2019) [5]; Gallone et al. (2020) [6]

Metabolic	Mechanical	Idiopathic	Genetic conditions*
Hypothyroidism	Scleroderma	Abnormal anatomy	Lysosomal storage diseases
Growth hormone	Physical activity	Obesity	MPS**
Pseudohypoparathyroidism	Fibrolipomatous hamartoma	Sports (golf, weight lifting, and basketball)	ML**
	Intraneural perineurioma	Playing instruments	Hunter syndrome**
	Hemangioma of the median nerve		Hurler syndrome**
	Macrodactyly		Congenital bone and muscle anomalies
	Fibrolipomas		Syndrome of HNPP
			Down syndrome
			Hemophilia
			Schwartz-Jampel syndrome
			Primary familial carpal tunnel syndrome
			Albright hereditary osteodystrophy
			Acromicric dysplasia
			Multiple xanthomas associated with familial hypercholesterolemia
			Klippel-Trénaunay syndrome
			Congenital constriction band syndrome